https://scholars.lib.ntu.edu.tw/handle/123456789/514506
標題: | Usefulness of lymphoscintigraphy in demonstrating lymphedema in patients with Noonan syndrome | 作者: | MEI-FANG CHENG YEN-WEN WU KAI-YUAN TZEN RUOH-FANG YEN |
公開日期: | 2008 | 卷: | 33 | 期: | 3 | 起(迄)頁: | 226-227 | 來源出版物: | Clinical Nuclear Medicine | 摘要: | Lymphatic dysplasia/hypoplasia is found in 15% to 20% of patients with Noonan syndrome. We report a 16-year-old boy with a classic phenotype of Noonan syndrome but a normal karyotype in chromosomal study. During the last 5 years, he had progressive bilateral lower limb edema. The microfilaria study, duplex sonography, and MRI of the lower extremities were all unremarkable. But lymphoscintigraphy showed stocking-like dermal backflow in both legs, delayed lymphatic flow to the inguinal nodes, and dilated lymphatic channels in the abdomen and thorax. These findings suggest that lymphoscintigraphy may be useful in providing vital information on the lymphatic drainage for patients with Noonan syndrome. ? 2008 Lippincott Williams & Wilkins, Inc. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/514506 | ISSN: | 0363-9762 | DOI: | 10.1097/RLU.0b013e3181597653 | SDG/關鍵字: | technetium sulfur colloid tc 99m; adolescent; article; case report; chromosome; congenital heart disease; disease duration; echography; face dysmorphia; human; inguinal lymph node; karyotype; leg; lymphadenopathy; lymphangiectasis; lymphedema; lymphoscintigraphy; male; Microfilaria; Noonan syndrome; nuclear magnetic resonance imaging; peripheral edema; phenotype; short stature; thorax disease; Adolescent; Humans; Lymphedema; Male; Noonan Syndrome |
顯示於: | 醫學院附設醫院 (臺大醫院) |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。