|Title:||Increasing stroke incidence and prevalence of risk factors in a low-income Chinese population||Authors:||Wang J.
|Issue Date:||2015||Publisher:||Lippincott Williams and Wilkins||Journal Volume:||84||Journal Issue:||4||Start page/Pages:||374-381||Source:||Neurology||Abstract:||
Objective: We investigated secular trends in incidence of first-ever stroke and the prevalence of stroke risk factors within the same population in rural China. Methods: In 1985, 15,438 residents from a township of Tianjin, China, were recruited to the Tianjin Brain Study, a population-based stroke surveillance study. Stroke events and all deaths were registered annually. Because imaging technology was first available in 1992, we analyzed the incidence of first-ever stroke over 3 study periods-1992-998, 1999-2005, and 2006-2012-from 1992 to 2012. Risk factor surveys were conducted in 1991 and 2011. Results: The age-standardized incidence of first-ever stroke per 100,000 person-years increased rapidly from 124.5 in 1992-1998 to 190.0 in 1999-2005 and to 318.2 in 2006-2012; incidence increased annually by 6.5% overall and by 12%among men aged 45-64 years (p < 0.05). From 1992 to 2012, the age at first-ever stroke in men was earlier by 3.3 years overall, but a similar trend was not observed in women. Concurrently, the prevalence of high fasting glucose and alcohol consumption increased significantly in both men and women, especially in men aged <45 years; the prevalence of obesity and high fasting glucose increased by 8.8-fold and 11-fold, respectively, from 1992 to 2012. Conclusions: The incidence of stroke in rural China increased rapidly, particularly among middleaged adults, along with a concurrent increase in risk factor prevalence. These findings suggest that without controlling these risk factors, stroke incidence will continue to increase over future decades in China. ? 2014 American Academy of Neurology.
|ISSN:||0028-3878||DOI:||10.1212/WNL.0000000000001175||SDG/Keyword:||glucose; adult; aged; alcohol consumption; Article; cerebrovascular accident; China; Chinese; female; follow up; growth; human; incidence; lowest income group; major clinical study; male; obesity; prevalence; priority journal; risk factor; rural area; middle aged; mortality; onset age; poverty; risk factor; rural population; statistics and numerical data; Stroke; Adult; Age of Onset; Aged; China; Female; Humans; Incidence; Male; Middle Aged; Poverty; Prevalence; Risk Factors; Rural Population; Stroke
|Appears in Collections:||醫學系|
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