https://scholars.lib.ntu.edu.tw/handle/123456789/514921
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | KUO-LIONG CHIEN | en_US |
dc.contributor.author | Sung F.-C. | en_US |
dc.contributor.author | CHIA-LUN CHAO | en_US |
dc.contributor.author | TA-CHEN SU | en_US |
dc.contributor.author | MING-FONG CHEN | en_US |
dc.contributor.author | Lee Y.-T. | en_US |
dc.creator | Chien K.-L.;Sung F.-C.;Chao C.-L.;Ta-Chen Su;Chen M.-F.;Lee Y.-T. | - |
dc.date.accessioned | 2020-09-28T02:48:08Z | - |
dc.date.available | 2020-09-28T02:48:08Z | - |
dc.date.issued | 2000 | - |
dc.identifier.issn | 0008-6312 | - |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0033798321&doi=10.1159%2f000007017&partnerID=40&md5=517872e74bb0cb0bbbcfae430b6d2bef | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/514921 | - |
dc.description.abstract | Twenty-eight coronary artery disease patients with more than 50% stenosis in at least one major coronary artery completed this randomized crossover clinical trial for the comparison of efficacy and safety of Nitrolingual-Spray and nitroglycerin (NTG) tablets. Exercise time was lengthened to 399.1 s (spray) or 408.5 s (tablets), compared to a baseline of 387.3 s. Ischemic burden decreased to about -4.0 mm with both forms, compared to -7.5 mm at baseline (ANOVA: p = 0.003). The ischemic time improved to 137.2 s (spray) or 152.9 s (tablets), compared to 253.4 s at baseline (ANOVA: p = 0.005). Patients taking tablets experienced more episodes of hypotension and/or headache compared to patients taking the spray. Nitrolingual-Spray is as effective and safe as NTG tablets for the treatment of symptomatic coronary heart disease. Copyright (C) 2000 S. Karger AG, Basel. | en_US |
dc.publisher | S. Karger AG | en_US |
dc.relation.ispartof | Cardiology | en_US |
dc.subject | Clinical trial; Coronary artery disease; Nitroglycerin; Treadmill exercise test | en_US |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | glyceryl trinitrate; nitrolingual spray; adult; aerosol; aged; article; clinical article; clinical trial; controlled clinical trial; controlled study; coronary artery disease; crossover procedure; drug efficacy; drug safety; exercise test; female; headache; human; hypotension; male; priority journal; randomized controlled trial; tablet; treadmill exercise; vertigo | - |
dc.title | A randomized crossover evaluation of antianginal efficacy and safety of nitrolingual-spray and nitroglycerin tablet form in coronary artery disease patients | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1159/000007017 | - |
dc.identifier.pmid | 10965083 | - |
dc.identifier.scopus | 2-s2.0-0033798321 | - |
dc.relation.pages | 137-141 | en_US |
dc.relation.journalvolume | 93 | en_US |
dc.relation.journalissue | 3 | en_US |
item.cerifentitytype | Publications | - |
item.fulltext | no fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.openairetype | journal article | - |
item.grantfulltext | none | - |
crisitem.author.dept | Epidemiology and Preventive Medicine | - |
crisitem.author.dept | Public Health | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUHHC | - |
crisitem.author.dept | Environmental and Occupational Medicine | - |
crisitem.author.dept | Environmental and Occupational Medicine-NTUH | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.orcid | 0000-0003-4979-8351 | - |
crisitem.author.orcid | 0000-0002-2804-7447 | - |
crisitem.author.orcid | 0000-0001-7523-7166 | - |
crisitem.author.orcid | 0000-0001-6633-7632 | - |
crisitem.author.parentorg | College of Public Health | - |
crisitem.author.parentorg | College of Public Health | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | NTU Hsin-Chu Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
顯示於: | 醫學系 |
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