https://scholars.lib.ntu.edu.tw/handle/123456789/515086
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | Wang W.-J. | en_US |
dc.contributor.author | CHIA-TER CHAO | en_US |
dc.contributor.author | Huang Y.-C. | en_US |
dc.contributor.author | Wang C.-Y. | en_US |
dc.contributor.author | Chang C.-H. | en_US |
dc.contributor.author | TAO-MIN HUANG | en_US |
dc.contributor.author | CHUN-FU LAI | en_US |
dc.contributor.author | Huang H.-Y. | en_US |
dc.contributor.author | Shiao C.-C. | en_US |
dc.contributor.author | TZONG-SHINN CHU | en_US |
dc.contributor.author | YUNG-MING CHEN | en_US |
dc.contributor.author | VIN-CENT WU | en_US |
dc.contributor.author | Ko W.-J. | en_US |
dc.contributor.author | KWAN-DUN WU | en_US |
dc.date.accessioned | 2020-09-28T07:04:46Z | - |
dc.date.available | 2020-09-28T07:04:46Z | - |
dc.date.issued | 2014 | - |
dc.identifier.issn | 0884-0431 | - |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84894478674&doi=10.1002%2fjbmr.2061&partnerID=40&md5=ae454a91413f399c917b3c22db5b5e70 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/515086 | - |
dc.description.abstract | Acute kidney injury (AKI) has a negative impact on long-term renal function and prognosis. However, the association between acute renal dysfunction and long-term effects on bone disorders has not yet been characterized. Using a population-based cohort study, we aimed to evaluate associations between AKI and long-term effects on bone fractures. We identified relevant data of all hospitalized patients aged >18 years with histories of dialysis-requiring AKI, with subsequent recovery and discharge, from the claim records of the Taiwan National Health Insurance database between 2000 and 2008. We determined long-term de novo bone fracture and all-cause mortality after patients' index-hospitalization discharge using propensity score-adjusted Cox proportional hazard model. Varying-time models were used to adjust for long-term effects of end-stage renal disease (ESRD) on main outcomes. Among 448 AKI patients who had dialysis and survived 90 days after index-hospitalization discharge without reentering dialysis, 273 were male (60.9%) with a mean age of 61.4 ± 16.6 years. Controls included 1792 hospitalized patients without AKI, dialysis, or bone fracture history. In the AKI recovery group, bone fracture incidence was 320 per 10,000 person-years and hazard ratio (HR) of long-term bone fracture was 1.25 (p = 0.049) compared with the control group, independent of subsequent ESRD status (HR = 1.55; p = 0.01). Both AKI recovery status (HR = 2.31; p < 0.001) and time varying factor of bone fracture (HR = 1.43; p < 0.001) were independent predictors of mortality compared with controls. In conclusion, AKI requiring temporary dialysis independently increases long-term risk of bone fracture, regardless of subsequent progression to ESRD. Long-term bone fractures may negatively impact patient mortality. ? 2014 American Society for Bone and Mineral Research. | en_US |
dc.relation.ispartof | Journal of Bone and Mineral Research | en_US |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | ACUTE KIDNEY INJURY; BONE FRACTURE; DIALYSIS; POPULATION; Acute Kidney Injury; Aged; Female; Fractures, Bone; Humans; Male; Middle Aged; Proportional Hazards Models; Renal Dialysis; Taiwan | - |
dc.title | The impact of acute kidney injury with temporary dialysis on the risk of fracture | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1002/jbmr.2061 | - |
dc.identifier.pmid | 23929760 | - |
dc.identifier.scopus | 2-s2.0-84894478674 | - |
dc.relation.pages | 676-684 | en_US |
dc.relation.journalvolume | 29 | en_US |
dc.relation.journalissue | 3 | en_US |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.openairetype | journal article | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
item.fulltext | no fulltext | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Internal Medicine-NTUHBH | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Internal Medicine-NTUHHC | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Medical Education and Bioethics | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Geriatrics and Gerontology-NTUH | - |
crisitem.author.dept | National Taiwan University Hospital Bei-Hu Branch | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Medicine-NTUCC | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.orcid | 0000-0003-2892-7986 | - |
crisitem.author.orcid | 0000-0002-9387-0798 | - |
crisitem.author.orcid | 0000-0003-2109-1522 | - |
crisitem.author.orcid | 0000-0002-5291-2509 | - |
crisitem.author.orcid | 0000-0002-9241-1258 | - |
crisitem.author.orcid | 0000-0001-7935-0991 | - |
crisitem.author.orcid | 0000-0002-3339-1509 | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital Bei-Hu Branch | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | NTU Hsin-Chu Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Cancer Center (NTUCC) | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
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