https://scholars.lib.ntu.edu.tw/handle/123456789/515134
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | VIN-CENT WU | en_US |
dc.contributor.author | CHUN-FU LAI | en_US |
dc.contributor.author | Shiao, Chih-Chung | en_US |
dc.contributor.author | YU-FENG LIN | en_US |
dc.contributor.author | Wu, Pei-Chen | en_US |
dc.contributor.author | CHIA-TER CHAO | en_US |
dc.contributor.author | Hu, Fu-Chang | en_US |
dc.contributor.author | TAO-MIN HUANG | en_US |
dc.contributor.author | YU-CHANG YEH | en_US |
dc.contributor.author | I-JUNG TSAI | en_US |
dc.contributor.author | Kao, Tze -Wah | en_US |
dc.contributor.author | YIN-YI HAN | en_US |
dc.contributor.author | Wu, Wen-Chung | en_US |
dc.contributor.author | Hou, Chun-Cheng | en_US |
dc.contributor.author | Young, Guang-Huar | en_US |
dc.contributor.author | Ko, Wen-Je | en_US |
dc.contributor.author | TUN-JUN TSAI | en_US |
dc.contributor.author | KWAN-DUN WU | en_US |
dc.date.accessioned | 2020-09-28T07:04:56Z | - |
dc.date.available | 2020-09-28T07:04:56Z | - |
dc.date.issued | 2012 | - |
dc.identifier.issn | 1932-6203 | - |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84863274609&doi=10.1371%2fjournal.pone.0030836&partnerID=40&md5=c588b27dfeef8d1c58b7f1d025cce3d1 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/515134 | - |
dc.description.abstract | Background: The impact of diuretic usage and dosage on the mortality of critically ill patients with acute kidney injury is still unclear. Methods and Results: In this prospective, multicenter, observational study, 572 patients with postsurgical acute kidney injury receiving hemodialysis were recruited and followed daily. Thirty-day postdialysis mortality was analyzed using Cox's proportional hazards model with time-dependent covariates. The mean age of the 572 patients was 60.8±16.6 years. Patients with lower serum creatinine (p = 0.031) and blood lactate (p = 0.033) at ICU admission, lower predialysis urine output (p = 0.001) and PaO 2/FiO 2 (p = 0.039), as well as diabetes (p = 0.037) and heart failure (p = 0.049) were more likely to receive diuretics. A total of 280 (49.0%) patients died within 30 days after acute dialysis initiation. The analysis of 30-day postdialysis mortality by fitting propensity score-adjusted Cox's proportional hazards models with time-dependent covariates showed that higher 3-day accumulated diuretic doses after dialysis initiation (HR = 1.449, p = 0.021) could increase the hazard rate of death. Moreover, higher time-varying 3-day accumulative diuretic doses were associated with hypotension (p<0.001) and less intense hemodialysis (p<0.001) during the acute dialysis period. Background and Significance: Higher time-varying 3-day accumulative diuretic dose predicts mortality in postsurgical critically ill patients requiring acute dialysis. Higher diuretic doses are associated with hypotension and a lower intensity of dialysis. Caution should be employed before loop diuretics are administered to postsurgical patients during the acute dialysis period. ? 2012 Wu et al. | en_US |
dc.relation.ispartof | PLoS ONE | en_US |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | creatinine; diuretic agent; lactic acid; diuretic agent; acute kidney failure; adult; aged; article; blood oxygen tension; cause of death; controlled study; creatinine blood level; critically ill patient; diabetes mellitus; dialysis; disease association; dose response; female; forced expiratory volume; heart failure; hemodialysis; hospital admission; human; hypotension; intensive care unit; major clinical study; male; mortality; multicenter study; postoperative complication; randomized controlled trial; scoring system; treatment duration; urine volume; blood pressure; clinical trial; critical illness; demography; drug effect; middle aged; mortality; proportional hazards model; prospective study; renal replacement therapy; risk factor; statistical model; survival; time; Blood Pressure; Critical Illness; Demography; Diuretics; Dose-Response Relationship, Drug; Female; Humans; Logistic Models; Male; Middle Aged; Proportional Hazards Models; Prospective Studies; Renal Dialysis; Risk Factors; Survival Analysis; Time Factors | - |
dc.title | Effect of diuretic use on 30-day postdialysis mortality in critically ill patients receiving acute dialysis | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1371/journal.pone.0030836 | - |
dc.identifier.pmid | 22431960 | - |
dc.identifier.scopus | 2-s2.0-84863274609 | - |
dc.relation.pages | e30836 | en_US |
dc.relation.journalvolume | 7 | en_US |
dc.relation.journalissue | 3 | en_US |
item.fulltext | no fulltext | - |
item.openairetype | journal article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Medicine-NTUCC | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Internal Medicine-NTUHBH | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Internal Medicine-NTUHHC | - |
crisitem.author.dept | Anesthesiology-NTUH | - |
crisitem.author.dept | Anesthesiology | - |
crisitem.author.dept | Pediatrics | - |
crisitem.author.dept | Pediatrics-NTUH | - |
crisitem.author.dept | Anesthesiology | - |
crisitem.author.dept | Traumatology-NTUH | - |
crisitem.author.dept | Surgery | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.orcid | 0000-0001-7935-0991 | - |
crisitem.author.orcid | 0000-0003-2109-1522 | - |
crisitem.author.orcid | 0000-0002-4350-7755 | - |
crisitem.author.orcid | 0000-0003-2892-7986 | - |
crisitem.author.orcid | 0000-0002-9387-0798 | - |
crisitem.author.orcid | 0000-0001-5143-5520 | - |
crisitem.author.orcid | 0000-0003-3967-9412 | - |
crisitem.author.orcid | 0000-0001-8831-7835 | - |
crisitem.author.orcid | 0000-0002-1666-8940 | - |
crisitem.author.orcid | 0000-0002-3339-1509 | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Cancer Center (NTUCC) | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital Bei-Hu Branch | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | NTU Hsin-Chu Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
顯示於: | 醫學系 |
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