https://scholars.lib.ntu.edu.tw/handle/123456789/515670
Title: | Distal Enteral Feeding Helps Blood Sugar Control in Pancreatectomized Patients | Authors: | JIN-MING WU CHING-YAO YANG TING-CHUN KUO HONG-SHIEE LAI Chiang P.-Y. Hsieh S.-H. YU-WEN TIEN |
Issue Date: | 2015 | Journal Volume: | 39 | Journal Issue: | 11 | Start page/Pages: | 2771-2775 | Source: | World Journal of Surgery | Abstract: | Background: The change in the route of food passage after pancreaticoduodenectomy (PD) is quite similar to the change after gastric bypass surgery; both procedures bypass the duodenum and directly connect to the distal jejunum. Moreover, both procedures result in resolution of type 2 diabetes mellitus. Therefore, more distal enteral anastomosis after PD may further improve glycemic status. Methods: To test the effect of distal enteral feeding on glucose metabolism in patients after PD, we performed a meal test on 20 patients via a nasogastric tube [proximal feeding group (PFG)] on post-operative day 5 and then via an intra-operatively placed jejunostomy feeding tube [distal feeding group (DFG)] on post-operative day. Blood samples were assessed for hormones and glucose. Results: The AUC0-120 min levels of GLP-1, C-peptide, and insulin after distal feeding were significantly higher than after proximal feeding. The AUC0-120 min levels of glucose in the DFG were significantly lower than in the PFG. Conclusions: More distal enteral feeding contributed to better glucose metabolism after PD. ? 2015 Soci?t? Internationale de Chirurgie. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/515670 | ISSN: | 0364-2313 | DOI: | 10.1007/s00268-015-3157-7 | SDG/Keyword: | C peptide; glucagon like peptide 1; glucose blood level; insulin; adult; aged; blood; digestive tract intubation; enteric feeding; female; glucose blood level; human; jejunostomy; male; metabolism; middle aged; pancreaticoduodenectomy; physiology; postprandial state; procedures; very elderly; Adult; Aged; Aged, 80 and over; Blood Glucose; C-Peptide; Enteral Nutrition; Female; Glucagon-Like Peptide 1; Humans; Insulin; Intubation, Gastrointestinal; Jejunostomy; Male; Middle Aged; Pancreaticoduodenectomy; Postprandial Period |
Appears in Collections: | 醫學院附設醫院 (臺大醫院) |
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