https://scholars.lib.ntu.edu.tw/handle/123456789/519191
標題: | Two-stage community-based screening model for estimating prevalence of diabetic polyneuropathy (KCIS No. 6) | 作者: | Hsu W.-C. Chiu Y.-H. Chiu H.-C. HORNG-HUEI LIOU Jeng Y.-C. Chen, Tony Hsiu Hsi |
公開日期: | 2005 | 卷: | 25 | 期: | 1 | 起(迄)頁: | 1-7 | 來源出版物: | Neuroepidemiology | 摘要: | The aim of this study was to apply a calibrated two-stage community-based design to estimate the prevalence of diabetic distal sensorimotor polyneuropathy (DPN) in Taiwan. Type 2 diabetics were identified from a population-based screening program in Keelung, Taiwan. Administration of the Neurological Symptom Score (NSS) questionnaire identified 210 DPN-positive cases of the 587 diabetic subjects tested. The accuracy of this NSS screening was tested with sensitive electrophysiological DPN diagnosis. A smaller validation study was also conducted to estimate the sensitivity and specificity of the NSS questionnaire. In the validation study, the overall prevalence rate for DPN among type 2 diabetics was 26.79%. The sensitivity, specificity, positive predictive value and negative predictive values were 73.33, 30.49, 24.72 and 75.76%, respectively. The estimates of sensitivity, specificity and positive predictive values were 75.00, 33.33 and 42.86% for old cases of diabetes, and 72.22, 29.69 and 22.41% for newly diagnosed cases. The range of prevalence rate in the main study was adjusted to 28.46-36.30% after calibration for sensitivity and specificity with the validation study data. A two-stage community-based screening model with calibration of prevalence rate was developed and enabled a cost-effective DPN prevalence rate estimate in a study with a large number of subjects. Copyright ? 2005 S. Karger AG. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-20844441617&doi=10.1159%2f000085306&partnerID=40&md5=36bcd2820e68e5e77b0e3676b3392e14 https://scholars.lib.ntu.edu.tw/handle/123456789/519191 |
DOI: | 10.1159/000085306 | SDG/關鍵字: | accuracy; adult; article; calibration; controlled study; diabetic neuropathy; female; human; major clinical study; male; non insulin dependent diabetes mellitus; prediction; prevalence; scoring system; screening; sensitivity and specificity; theoretical model; Aged; Diabetic Neuropathies; Female; Humans; Male; Mass Screening; Median Nerve; Middle Aged; Neural Conduction; Prevalence; Questionnaires; Reproducibility of Results; Sciatic Nerve; Sensitivity and Specificity; Taiwan; Ulnar Nerve |
顯示於: | 醫學系 |
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