https://scholars.lib.ntu.edu.tw/handle/123456789/519449
標題: | Predicting Neurodegenerative Diseases Using a Novel Blood Biomarkers-based Model by Machine Learning | 作者: | Chiu, S.-I. CHIN-HSIEN LIN Lim, W.S. MING-JANG CHIU TA-FU CHEN JYH-SHING JANG |
關鍵字: | Biomarkers; Classification; Linear discriminant analysis; Multivariate imputation by chained equations; Neurodegenerative disease | 公開日期: | 2019 | 出版社: | Institute of Electrical and Electronics Engineers Inc. | 來源出版物: | Proceedings - 2019 International Conference on Technologies and Applications of Artificial Intelligence, TAAI 2019 | 會議論文: | 24th International Conference on Technologies and Applications of Artificial Intelligence, TAAI 2019 | 摘要: | This paper presents machine learning based framework to the analysis and modeling of several neurodegenerative diseases by using features from blood-based biomarkers. The proposed approaches can be employed for early detection of Alzheimer's disease (AD) or Parkinson's disease (PD). In particular, we applied LDA (linear discriminant analysis) for visualizing the dataset as 2D or 3D scatter plots. Moreover, we constructed various classifiers for several different tasks of classification, and explore the accuracy of these classifiers. Based on our experiments, random forests are in general a very good choice of these tasks considering both the computing time (during modeling and prediction) and the accuracy. © 2019 IEEE. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85079036833&doi=10.1109%2fTAAI48200.2019.8959854&partnerID=40&md5=2fd06166dcf67d52be3c23e354793236 https://scholars.lib.ntu.edu.tw/handle/123456789/519449 |
DOI: | 10.1109/TAAI48200.2019.8959854 | SDG/關鍵字: | Biomarkers; Blood; Classification (of information); Decision trees; Discriminant analysis; Machine learning; Multivariant analysis; Alzheimer's disease; Analysis and modeling; Computing time; Linear discriminant analysis; Modeling and predictions; Multivariate imputation by chained equations; Parkinson's disease; Scatter plots; Neurodegenerative diseases |
顯示於: | 醫學系 |
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