https://scholars.lib.ntu.edu.tw/handle/123456789/520056
標題: | Cauda equina-conus medullaris syndrome as an isolated presenting symptom of intravascular large B-cell lymphoma: Case report and review of the literature | 作者: | MENG-CHEN WU CHIN-HSIEN LIN |
公開日期: | 2014 | 出版社: | ASEAN Neurological Association | 卷: | 19 | 期: | 2 | 起(迄)頁: | 219-225 | 來源出版物: | Neurology Asia | 摘要: | Intravascular large B-cell lymphoma (IVLBCL) is a rare non-Hodgkin lymphoma with variable clinical manifestations. Although neurological symptoms are common in patients with IVLBCL, isolated cauda equina-conus medullaris syndrome is rarely reported. We herein report a case of IVLBCL whose initial presentation was cauda equina-conus medullaris syndrome with neither dermatological nor hematological manifestations. A 54-year-old man without known immune-compromised state presented with progressive ascending numbness and weakness of bilateral legs and urine incontinence for 2 months. Lumbar-sacral magnetic resonance images showed gadolinium-enhanced conus medullaris and cauda equina nerve roots. Cerebrospinal fluid analysis revealed lymphocyte predominant pleocytosis and elevated protein level without malignant cells. Focal seizure and mental status changes followed several weeks later. Brain biopsy led to the diagnosis of IVLBCL. Conclusions: IVLBCL should be included in the differential diagnosis of patients with isolated cauda equina-conus medullaris syndrome. A survey of previously published cases in the literature also showed that early initiation of chemotherapy has better outcome. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84904289174&partnerID=40&md5=da981cc0d63f52b7ebca3ea72837c6aa https://scholars.lib.ntu.edu.tw/handle/123456789/520056 |
ISSN: | 1823-6138 | SDG/關鍵字: | CD20 antigen; CD79a antigen; cytarabine; gadolinium; interferon regulatory factor 4; lactate dehydrogenase; methotrexate; protein; rituximab; adult; article; brain biopsy; cancer chemotherapy; case report; cauda equina conus medullaris syndrome; cauda equina syndrome; cause of death; cerebrospinal fluid analysis; consciousness; contrast enhancement; drug megadose; flaccid paralysis; follow up; human; human tissue; hyperlipidemia; hypertension; kidney polycystic disease; lactate dehydrogenase blood level; large cell lymphoma; leg pain; limb weakness; male; middle aged; muscle strength; neurologic examination; nuclear magnetic resonance imaging; pancytopenia; paresthesia; pleocytosis; seizure; sensory dysfunction; sepsis; symptom; urine incontinence; white matter lesion |
顯示於: | 醫學系 |
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