https://scholars.lib.ntu.edu.tw/handle/123456789/520734
標題: | Frontotemporal dementia and motor neuron disease: Report of 3 cases in Taiwan and literature review | 作者: | KAI-HSIANG CHEN MING-JANG CHIU Cheng T.-W. JEN-JEN SU |
公開日期: | 2011 | 卷: | 20 | 期: | 3 | 起(迄)頁: | 202-208 | 來源出版物: | Acta Neurologica Taiwanica | 摘要: | Purpose: Case reports and a review of literature of the coexistence of motor neuron disease (MND) and frontotemporal dementia (FTD). Case Report: All three patients demonstrated generalized lower motor neuron signs and very few upper motor neuron signs. In the level of patterns of cognitive impairments, neuropsychological studies do not distinguish between patients with onset of weakness from bulbar palsy and patients with onset of weakness from limbs. All patients of FTD had their onset of MND or amyotrophic lateral sclerosis symptoms within a two-year interval which is similar to previous reports. FTD combined with MND may shorten the survival to less than three years shorter than cases with FTD only. Respiratory failure occurred one to two years after onset of the behavioral symptoms in all patients. Conclusion: We reported three patients of FTD with MND to remind clinicians that these two disorders may occur together on the same patient and that these two disorders may belong to one broad spectrum neurodegenerative disease. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-81855180680&partnerID=40&md5=2203f4338c031a39d7e07077351ac838 https://scholars.lib.ntu.edu.tw/handle/123456789/520734 |
ISSN: | 1019-6099 | SDG/關鍵字: | antidepressant agent; riluzole; abductor digiti minimi muscle; adult; airway obstruction; amyotrophic lateral sclerosis; anorexia; apathy; article; aspiration pneumonia; attention disturbance; behavior disorder; biceps brachii muscle; case report; daily life activity; defecation disorder; depression; disorientation; dysphagia; dysphoria; electromyography; episodic memory; frontal variant frontotemporal dementia; frontotemporal dementia; human; hyporeflexia; impulsiveness; irritability; job performance; limb weakness; male; memory disorder; motor neuron disease; muscle action potential; muscle atrophy; peroneus nerve; perseveration; personal hygiene; positive end expiratory pressure; psychosocial withdrawal; quadriceps femoris muscle; rectus femoris muscle; respiratory failure; restlessness; self neglect; semantic memory; septic shock; single photon emission computer tomography; skeletal muscle; stereotypy; survival time; tendon reflex; tibialis anterior muscle; tracheotomy; weight reduction; Amyotrophic Lateral Sclerosis; Frontotemporal Dementia; Humans; Male; Middle Aged; Motor Neuron Disease |
顯示於: | 醫學系 |
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