https://scholars.lib.ntu.edu.tw/handle/123456789/521165
標題: | Identification of novel loci for bipolar I disorder in a multi-stage genome-wide association study | 作者: | PO-HSIU KUO Chuang, L C Liu, J R CHIH-MIN LIU Huang, M C Lin, S K Sunny Sun, H MING-HSIEN HSIEH Hung Hung HSIU-PO KUO |
關鍵字: | Bipolar disorder; Genome-wide association; Rank-based method | 公開日期: | 3-六月-2014 | 出版社: | PERGAMON-ELSEVIER SCIENCE LTD | 卷: | 51 | 起(迄)頁: | 58 | 來源出版物: | Progress in neuro-psychopharmacology & biological psychiatry | 摘要: | Identification of genetic variants that influence bipolar I disorder (BPD-I) through genome-wide association (GWA) studies is limited in Asian populations. The current study aimed to identify novel common variants for BPD-I in an ethnically homogeneous Taiwanese sample using a multi-stage GWA study design. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/521165 | ISSN: | 0278-5846 | DOI: | 10.1016/j.pnpbp.2014.01.003 | SDG/關鍵字: | article; bipolar I disorder; controlled study; disease activity; disease association; gene; gene identification; gene locus; gene mapping; gene replication; genetic association; genetic marker; genetic variability; genotype; genotyping technique; human; KCNH7 gene; major clinical study; molecular dynamics; molecular pathology; MYST4 gene; NRXN3 gene; outcome assessment; patient assessment; promoter region; SEMA3D gene; single nucleotide polymorphism; syndrome delineation; adolescent; adult; aged; bipolar disorder; female; genetic association; genetic predisposition; genetics; male; middle aged; statistical model; Taiwan; young adult; histone acetyltransferase; KAT6B protein, human; KCNH7 protein, human; nerve protein; neurexin IIIalpha; potassium channel HERG; Sema3D protein, human; semaphorin; Adolescent; Adult; Aged; Bipolar Disorder; Ether-A-Go-Go Potassium Channels; Female; Genetic Predisposition to Disease; Genome-Wide Association Study; Genotype; Histone Acetyltransferases; Humans; Logistic Models; Male; Middle Aged; Nerve Tissue Proteins; Polymorphism, Single Nucleotide; Semaphorins; Taiwan; Young Adult |
顯示於: | 流行病學與預防醫學研究所 |
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