https://scholars.lib.ntu.edu.tw/handle/123456789/522056
標題: | Disseminated cytomegalovirus disease in a patient with systemic lupus erythematosus not undergoing immunosuppressive therapy | 作者: | SHIH-CHI KU CHONG-JEN YU YIH-LEONG CHANG PAN-CHYR YANG |
公開日期: | 1999 | 卷: | 98 | 期: | 12 | 起(迄)頁: | 855-858 | 來源出版物: | Journal of the Formosan Medical Association | 摘要: | We describe a case of cytomegalovirus (CMV) infection in a 25-year-old woman with a 3-year history of systemic lupus erythematosus (SLE) with persistently high disease activity, who had not received immunosuppressive therapy. Disseminated CMV infection presented with upper gastrointestinal bleeding, high fever, respiratory distress, leukopenia, and thrombocytopenia. The CMV infection was successfully treated with combined antiviral and immunoglobulin therapy, and the SLE activity decreased concomitantly. CMV disease is closely related to host immunosuppression, primarily T-lymphocyte dysfunction. This case should highlight the relationship between clinically significant CMV disease and compromised immunity in patients with active SLE who are not receiving immunosuppressive therapy. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0033372014&partnerID=40&md5=ac802804b937db862fcdf41c5cc34823 https://scholars.lib.ntu.edu.tw/handle/123456789/522056 |
ISSN: | 0929-6646 | SDG/關鍵字: | ganciclovir; immunoglobulin; adult; article; case report; clinical feature; Cytomegalovirus; cytomegalovirus infection; digestive system hemorrhage; disease association; female; fever; human; immunosuppressive treatment; leukopenia; respiratory distress; systemic lupus erythematosus; thrombocytopenia; Adult; Cytomegalovirus Infections; Female; Humans; Immunosuppressive Agents; Lupus Erythematosus, Systemic |
顯示於: | 醫學系 |
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