https://scholars.lib.ntu.edu.tw/handle/123456789/522092
標題: | YC-1 induces lipid droplet formation in RAW 264.7 macrophages | 作者: | Tsui, Leo Chang, Shwu-Fen HSIANG-PO HUANG Fong, Tsorng-Harn I-JONG WANG |
關鍵字: | Macrophages; Foam cells; Oxidized low density lipoproteins; YC-1; cGMP-dependent protein kinase | 公開日期: | 15-一月-2016 | 出版社: | BIOMED CENTRAL LTD | 卷: | 23 | 期: | 1 | 來源出版物: | Journal of biomedical science | 摘要: | 3-(5'-Hydroxymethyl-2'-furyl)-1-benzylindazole (YC-1) is a potential anticancer drug that may activate soluble guanylyl cyclase (sGC) and increase the level of cyclic guanosine monophosphate (cGMP). The aim of this study was to explore the effects of YC-1 on lipid droplet accumulation and foam cell formation in macrophages. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/522092 | ISSN: | 1423-0127 | DOI: | 10.1186/s12929-016-0218-7 |
顯示於: | 基因體暨蛋白體醫學研究所 |
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