https://scholars.lib.ntu.edu.tw/handle/123456789/522993
標題: | Effectiveness of the medication safety review clinics for older adults prescribed multiple medications | 作者: | DING-CHENG CHAN JEN-HAU CHEN Chiung-Jung Wen Chiu L.-S. Wu S.-C. |
公開日期: | 2014 | 卷: | 113 | 期: | 2 | 起(迄)頁: | 106-113 | 來源出版物: | Journal of the Formosan Medical Association | 摘要: | Background/Purpose: Polypharmacy is common among Taiwanese older adults. We aim to determine the effectiveness of the medication safety review clinics (MSRCs) for solving drug-related problems (DRPs) among older adults prescribed multiple medications. Methods: This prospective case-series intervention study was conducted at the outpatient department of the National Taiwan University Hospital and its BeiHu Branch. Older adults (?65 years) who either had been prescribed ?8 chronic medications (drugs prescribed for ?28 days) or had visited ?3 different physicians during the 3-month screening period were enrolled (N=193). DRPs were identified after baseline assessments from a team of geriatricians and pharmacists. Prescribers were contacted with proposed interventions to be administered within 12 weeks. Problem-solving rates (PSRs) at both Week 12 and Week 24 visits were recorded. Stepwise multivariate logistic regression was applied to identify correlates of having at least one unsolved DRP at 24 weeks. Participants (N=139) who completed four visits to the MSRCs were analyzed. Results: The mean age was 75.6±6.1 years and 56% of them were men. The mean chronic medication per patient was 9.0±3.1, and the mean DRP per patient was 2.1±1.5. ThePSR was 76% at Week 12 and 87% at Week 24. Thirty-two patients (22%) had at least one unsolved DRP. Correlates of the unsolved DRP included a higher geriatric depression scale, a higher chronic medication per patient, and a higher DRP per patient. The mean chronic medication per patient (9.0 vs. 8.6, p<0.05) decreased, and the number of participants rating good or better health status improved from 22% to 38% in 24 weeks (p<0.001). Participants were highly satisfied (96% at all times) with the service. Conclusion: DRPs were common in geriatric outpatients taking multiple medications and most were solved with appropriate interventions. The MSRC service may improve prescription quality in Taiwan if widely available. ? 2012. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84893972955&doi=10.1016%2fj.jfma.2012.04.013&partnerID=40&md5=16b53a3d96c48eeb36aac2c9d6fc5b81 https://scholars.lib.ntu.edu.tw/handle/123456789/522993 |
ISSN: | 0929-6646 | DOI: | 10.1016/j.jfma.2012.04.013 | SDG/關鍵字: | aged; drug-related problems; medication review; outpatient; polypharmacy; Aged; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Male; Medication Therapy Management; Outpatients; Polypharmacy; Taiwan |
顯示於: | 醫學系 |
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