https://scholars.lib.ntu.edu.tw/handle/123456789/523917
Title: | Diffuse alveolar damage associated with ticlopidine use: A case report | Authors: | Oon P.-C. JIH-SHUIN JERNG HSIEN-LI KAO YIH-LEONG CHANG CHONG-JEN YU PAN-CHYR YANG |
Issue Date: | 2003 | Journal Volume: | 102 | Journal Issue: | 4 | Start page/Pages: | 262-265 | Source: | Journal of the Formosan Medical Association | Abstract: | Ticlopidine-induced lung disease is rare. A 52-year-old man with acute myocardial infarction developed respiratory distress 2 days after receiving ticlopidine for coronary artery stenting. The dosage of ticlopidine was 500 mg orally followed by maintenance of 250 mg twice daily. Chest radiography revealed bilateral haziness predominantly over upper lung fields. He did not respond to treatment for suspected cardiogenic lung edema and mechanical ventilation was instituted. Open lung biopsy documented diffuse alveolar damage. After discontinuing ticlopidine and treatment with systemic corticosteroid, his pulmonary condition improved gradually. Within 2 weeks, the patient was successfully weaned from the ventilator. Although rare, diffuse alveolar damage is a potential side effect of ticlopidine treatment and should be included in the differential diagnoses of heart failure patients taking ticlopidine who respond poorly to optimal therapy. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0041411311&partnerID=40&md5=90331026dcfee6b8122c80ba023d811a https://scholars.lib.ntu.edu.tw/handle/123456789/523917 |
ISSN: | 0929-6646 | SDG/Keyword: | acetylsalicylic acid; amiodarone; azathioprine; captopril; ciprofloxacin; clopidogrel; colchicine; corticosteroid derivative; cytotoxic agent; diuretic agent; dobutamine; gold salt; heparin; inotropic agent; magnesium oxide; methylprednisolone; penicillamine; salazosulfapyridine; streptokinase; ticlopidine; acute heart infarction; adult; allergic pneumonitis; article; artificial ventilation; blood dyscrasia; bronchiolitis; case report; coronary stent; diarrhea; differential diagnosis; drug efficacy; drug induced disease; drug safety; drug withdrawal; fibrosing alveolitis; heart failure; hepatitis; hospital infection; human; interstitial lung disease; lung edema; lung function test; lung nodule; lymphocytic colitis; maintenance drug dose; male; nausea; neutropenia; obstructive jaundice; open lung biopsy; rash; thorax radiography; transluminal coronary angioplasty; ventilator; vomiting; Humans; Lung Diseases; Male; Middle Aged; Platelet Aggregation Inhibitors; Pulmonary Alveoli; Ticlopidine |
Appears in Collections: | 醫學系 |
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