https://scholars.lib.ntu.edu.tw/handle/123456789/524931
標題: | Body mass index may modify asthma prevalence among low-birth-weight children | 作者: | FRANK LEIGH LU Hsieh C.-J. Caffrey J.L. Lin M.-H. Lin Y.-S. CHINGCHUN LIN Tsai M.-S. Ho W.-C. PAU-CHUNG CHEN Sung F.-C. Lin R.-S. |
公開日期: | 2012 | 卷: | 176 | 期: | 1 | 起(迄)頁: | 32-42 | 來源出版物: | American Journal of Epidemiology | 摘要: | Childhood asthma, a growing health concern, has been associated with low birth weight and elevated body mass index. This study tested the hypothesis that overweight and obese adolescents with a history of low birth weight are at even greater risk of developing asthma. A cohort of 75,871 junior high school students was screened for asthma during 1995-1996 in Taiwan. Birth weight and estimated gestational age were obtained from the birth registry. Logistic regression and simple regression analyses were adjusted for confounding variables. Asthma was more prevalent in those with birth weights below 3,000 g and higher adolescent body mass indexes. Furthermore, those with both characteristics were consistently most likely to have asthma. Whether the asthma diagnosis among low-birth-weight subjects was assigned by physicians or medical questionnaire, the risks were elevated for both overweight (physician diagnosis: odds ratio = 1.41; medical questionnaire: odds ratio = 1.25) and obese (physician diagnosis: odds ratio = 1.38; medical questionnaire: odds ratio = 1.47) boys as well as overweight (physician diagnosis: odds ratio = 1.63; medical questionnaire: odds ratio = 1.30) and obese (physician diagnosis: odds ratio = 1.44; medical questionnaire: odds ratio = 1.32) girls (P < 0.05). Low birth weight predisposes one to develop asthma, and excess body mass amplifies the risk. A sex difference was observed. This study suggests that prenatal care and nutritional counseling could reduce asthma prevalence. ? The Author 2012. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84863310231&doi=10.1093%2faje%2fkwr484&partnerID=40&md5=9c3fb1cc88b24f8adb98cce3acfdd0c5 https://scholars.lib.ntu.edu.tw/handle/123456789/524931 |
ISSN: | 0002-9262 | DOI: | 10.1093/aje/kwr484 | SDG/關鍵字: | adolescence; asthma; body mass; child health; cohort analysis; disease prevalence; health risk; hypothesis testing; nutritional status; obesity; questionnaire survey; regression analysis; risk factor; sex-related difference; student; adolescent; article; asthma; body mass; cohort analysis; controlled study; disease course; female; gestational age; high school student; human; low birth weight; major clinical study; male; nutritional counseling; obesity; physician; prenatal care; prevalence; questionnaire; register; risk factor; Taiwan; Adolescent; Asthma; Body Mass Index; Child; Cross-Sectional Studies; Female; Health Surveys; Humans; Infant, Low Birth Weight; Infant, Newborn; Logistic Models; Male; Mass Screening; Obesity; Odds Ratio; Overweight; Prevalence; Registries; Respiratory Function Tests; Sex Factors; Taiwan; Taiwan |
顯示於: | 醫學系 |
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