https://scholars.lib.ntu.edu.tw/handle/123456789/525041
標題: | Permanent neonatal diabetes mellitus manifesting as diabetic ketoacidosis | 作者: | JYH-HONG LEE WEN-YU TSAI HUNG-CHIEH CHOU YI-CHING TUNG WU-SHIUN HSIEH |
公開日期: | 2003 | 卷: | 102 | 期: | 12 | 起(迄)頁: | 883-886 | 來源出版物: | Journal of the Formosan Medical Association | 摘要: | Neonatal diabetes mellitus (NDM) is very rare disease defined as hyperglycemia that occurs during the first month of life, requires insulin treament, and lasts more than 2 weeks. There are 2 types of NDM: permanent neonatal diabetes mellitus (PNDM) and transient neonatal diabetes mellitus (TNDM). We report a case of PNDM in a 3-day-old female infant. This full-term neonate was born small gestational age. Respiratory distress, poor activity, hypothermia, poor feeding, dehydration, and ketoacidosis were noted at the age of 3 days. After insulin therapy and fluid replacement, her condition became stable. Glucagon test done at the age of 26 days showed serum C-peptide level to be low for her age. During the first year of life she had catch-up growth, but insulin therapy was still required. Serum C-peptide level was undertectable at the age of 15 months. The course of this case indicates the important and facilitate normal growth and development under insulin therapy. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-2342585532&partnerID=40&md5=d4b5809724115c8b454cccc5e50c2dc7 https://scholars.lib.ntu.edu.tw/handle/123456789/525041 |
ISSN: | 0929-6646 | SDG/關鍵字: | C peptide; glucagon; glucose; isophane insulin; article; case report; catch up growth; child development; child growth; clinical feature; dehydration; diabetes mellitus; diabetic ketoacidosis; disease course; disease duration; feeding disorder; female; fluid therapy; human; hyperglycemia; hypothermia; infant; physical activity; respiratory distress; small for date infant; treatment outcome; Diabetes Mellitus; Diabetic Ketoacidosis; Diagnosis, Differential; Female; Humans; Infant, Newborn |
顯示於: | 醫學系 |
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