https://scholars.lib.ntu.edu.tw/handle/123456789/525599
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | Su W.-J. | en_US |
dc.contributor.author | PEI-LAN SHAO | en_US |
dc.contributor.author | Liu M.-T. | en_US |
dc.contributor.author | DING-PING LIU | en_US |
dc.contributor.author | KUO-CHIN HUANG | en_US |
dc.contributor.author | LUAN-YIN CHANG | en_US |
dc.contributor.author | CHUN-YI LU | en_US |
dc.contributor.author | Wang J.-R. | en_US |
dc.contributor.author | Shih S.-R. | en_US |
dc.contributor.author | Huang D.T.-N. | en_US |
dc.contributor.author | Chi H. | en_US |
dc.contributor.author | LI-MIN HUANG | en_US |
dc.creator | Su W.-J.;Shao P.-L.;Liu M.-T.;Liu D.-P.;Huang K.-C.;Luan-Yin Chang;Lu C.-Y.;Wang J.-R.;Shih S.-R.;Huang D.T.-N.;Chi H.;Huang L.-M. | - |
dc.date.accessioned | 2020-12-15T07:42:16Z | - |
dc.date.available | 2020-12-15T07:42:16Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 1058-4838 | - |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-77954697540&doi=10.1086%2f653532&partnerID=40&md5=485f8e49ec6508f4bde2138a4aa21893 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/525599 | - |
dc.description.abstract | Background. Our objective was to determine the serological signals that indicated the possible dominant circulating influenza virus subtypes for the coming influenza seasons. Methods. Healthy children 6 months through 5 years of age, adults 18-60 years of age, and elderly adults >60 years of age were recruited to receive seasonal trivalent inactivated influenza vaccinations from October through December during the 2006-2007 and 2008-2009 seasons. Paired serum samples were collected at baseline and at 3 weeks after vaccination. Using a hemagglutination inhibition (HAI) assay, we measured antibody responses to local influenza strains circulating early in October, before each winter influenza season. Results. A total of 301 subjects were tested for antibody to local strains (80, 120, and 101 subjects in the 2006-2007, 2007-2008, and 2008-2009 seasons, respectively). The dominant winter influenza strains in Taiwan were B/Malaysia/2506/2004-like in the 2006-2007 season, A/Brisbane/59/2007-like virus (H1N1) in the 2007-2008 season, and A/Brisbane/59/2007-like virus (H1N1) in the 2008-2009 season. The group with the lowest number of subjects with an HAI titer of ?40 at baseline was children with antibody against the B/Taiwan/0050/2006 in the 2006-2007 season, A/Taiwan/785/2006 (H1N1) in 2007-2008 season, and A/Taiwan/951/2007 (H1N1) in 2008- 2009 season. The emergence of these viruses correlated well with the circulating influenza subtype in the following winter peak seasons. Conclusions. Low seroprotection rate among children against a specific locally circulating influenza strain might predict the dominantly circulating subtype of influenza virus in the coming winter season. A year-end preseasonal serological survey of children could provide valuable information about the possible circulating strain and tailor the disease-control strategy accordingly. ? 2010 by the Infectious Diseases Society of America. All rights reserved. | - |
dc.publisher | University of Chicago Press | - |
dc.relation.ispartof | Clinical Infectious Diseases | - |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | inactivated virus vaccine; influenza vaccine; influenza vaccine; virus antibody; adolescent; adult; antibody response; antibody titer; article; blood sampling; child; epidemic; hemagglutination inhibition test; human; infant; Influenza virus A H1N1; Influenza virus A H3N2; major clinical study; predictor variable; preschool child; priority journal; school child; seasonal influenza; serology; Taiwan; vaccination; virus strain; winter; aged; blood; classification; immunology; Influenza, Human; isolation and purification; male; middle aged; Orthomyxovirus; very elderly; young adult; Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Viral; Child, Preschool; Hemagglutination Inhibition Tests; Humans; Infant; Influenza Vaccines; Influenza, Human; Male; Middle Aged; Orthomyxoviridae; Taiwan; Young Adult | - |
dc.title | Low seroprotection against preseasonal influenza local strains in children might predict the upcoming epidemic influenza strains | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1086/653532 | - |
dc.identifier.pmid | 20528478 | - |
dc.identifier.scopus | 2-s2.0-77954697540 | - |
dc.relation.pages | 171-176 | - |
dc.relation.journalvolume | 51 | - |
dc.relation.journalissue | 2 | - |
item.fulltext | no fulltext | - |
item.grantfulltext | none | - |
item.openairetype | journal article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.cerifentitytype | Publications | - |
crisitem.author.dept | Laboratory Medicine | - |
crisitem.author.dept | Pediatrics-NTUHHC | - |
crisitem.author.dept | Laboratory Medicine-NTUHHC | - |
crisitem.author.dept | Epidemiology and Preventive Medicine | - |
crisitem.author.dept | Family Medicine | - |
crisitem.author.dept | Family Medicine-NTUH | - |
crisitem.author.dept | Health Behaviors and Community Sciences | - |
crisitem.author.dept | Psychology | - |
crisitem.author.dept | Pediatrics | - |
crisitem.author.dept | Pediatrics | - |
crisitem.author.dept | Pediatrics-NTUH | - |
crisitem.author.dept | Pediatrics | - |
crisitem.author.dept | Epidemiology and Preventive Medicine | - |
crisitem.author.dept | National Taiwan University Children's Hospital | - |
crisitem.author.dept | Pediatrics-NTUH | - |
crisitem.author.orcid | 0000-0003-3334-1330 | - |
crisitem.author.orcid | 0000-0002-8596-3572 | - |
crisitem.author.orcid | 0000-0002-6029-5520 | - |
crisitem.author.orcid | 0000-0003-2632-1956 | - |
crisitem.author.orcid | 0000-0002-5240-2808 | - |
crisitem.author.orcid | 0000-0002-9291-260X | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | NTU Hsin-Chu Hospital | - |
crisitem.author.parentorg | NTU Hsin-Chu Hospital | - |
crisitem.author.parentorg | College of Public Health | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Public Health | - |
crisitem.author.parentorg | College of Science | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Public Health | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
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