https://scholars.lib.ntu.edu.tw/handle/123456789/526024
標題: | Fundus abnormalities in a patient with type I Gaucher's disease with 12-year follow-up | 作者: | Wang T.-J. MUH-SHY CHEN Shih Y.-F. WUH-LIANG HWU Lai M.-Y. |
公開日期: | 2005 | 出版社: | Elsevier Inc. | 卷: | 139 | 期: | 2 | 起(迄)頁: | 359-362 | 來源出版物: | American Journal of Ophthalmology | 摘要: | Purpose: To report a case of type I Gaucher's disease with rare presentation of fundus abnormalities in long-term observation. Design: Observational case report. Methods: This 53-year-old Taiwanese woman suffered from type I Gaucher's disease for 12 years, with initial presentation of hepatoslpenomegaly in 1992. Results: At that time, poor vision with unusual macular change and peripheral retinal vessel leakage was also noted. She received a complete ophthalmic examination at the initial visit and again 12 years later in 2003. She was treated with imiglucerase injection during the last 4 years. However, her visual acuity was 10/200 in both eyes. The macular and peripheral retinal degenerative change progressed after 12 years. Conclusions: Fundus changes associated with Gaucher's disease are uncommon. We should not neglect the possibility of retinal involvement and progression in these patients. ? 2005 by Elsevier Inc. All rights reserved. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-14244253671&doi=10.1016%2fj.ajo.2004.07.053&partnerID=40&md5=b87176ef585edc293b99b6626145f308 https://scholars.lib.ntu.edu.tw/handle/123456789/526024 |
ISSN: | 0002-9394 | DOI: | 10.1016/j.ajo.2004.07.053 | SDG/關鍵字: | imiglucerase; adult; article; case report; disease course; eye fundus; female; follow up; Gaucher disease; hepatosplenomegaly; human; ophthalmoscopy; priority journal; retina injury; retina macula degeneration; visual acuity; visual disorder |
顯示於: | 醫學系 |
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