https://scholars.lib.ntu.edu.tw/handle/123456789/526488
標題: | Development of acute lymphoblastic leukemia in a child after treatment of langerhans cell histiocytosis: Report of one case | 作者: | Wu J.-H. MENG-YAO LU KAI-HSIN LIN SHIANN-TANG JOU DONG-TSAMN LIN |
公開日期: | 1999 | 卷: | 40 | 期: | 6 | 起(迄)頁: | 441-442 | 來源出版物: | Acta Paediatrica Taiwanica | 摘要: | Langerhans cell histiocytosis (LCH) is a group of poorly understood disorders. To our knowledge, LCH is a non-malignant disorder. The association of LCH with a secondary neoplasm has not been well assessed, however, a few cases have been reported. We report a case of LCH, a localized osteolytic lesion over metaphysis of left femur, who was treated with local curettage and chemotherapy with vincristine, prednislone and 6-mercaptopurine (6-MP) for eight months from end of 1991 to August, 1992. Six years later, she had acute lymphoblastic leukemia (ALL) in 1998. In review of current literature, only 5 cases of LCH, including our case, have preceded ALL. The possible association, a reactive process or a therapy-related process, between LCH and acute leukemia is still unclear at present and needs to be explored by more studies in the future. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0033491242&partnerID=40&md5=fbdc8ee5b39b22df985d05cbc5d408f6 https://scholars.lib.ntu.edu.tw/handle/123456789/526488 |
ISSN: | 0001-6578 | SDG/關鍵字: | mercaptopurine; prednisolone; vincristine; acute lymphoblastic leukemia; article; case report; child; curettage; disease association; drug induced cancer; drug safety; female; histiocytosis X; human; preschool child; second cancer; Female; Histiocytosis, Langerhans-Cell; Humans; Infant; Leukemia, Lymphocytic, Acute, L1 |
顯示於: | 醫學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。