https://scholars.lib.ntu.edu.tw/handle/123456789/526492
標題: | Evaluation of a live attenuated varicella vaccine in 15- to 18-month-old healthy children | 作者: | MENG-YAO LU | 關鍵字: | Measles; Mumps; Rubella; Vaccine; Varicella-zoster virus | 公開日期: | 1998 | 卷: | 39 | 期: | 1 | 起(迄)頁: | 38-42 | 來源出版物: | Acta Paediatrica Sinica | 摘要: | A clinical trial was conducted in Taiwan in 15- to 18- month-old healthy children to study the reactogenicity and immunogenicity of live varicella vaccine combined with standard measles-mumps-rubella vaccine. A total of 118 varicella antibody-negative children were enrolled. They received one dose of varicella vaccine and one dose of measles-mumps-rubella vaccine at the same time. The vaccines were well tolerated; adverse reactions were mild and infrequent, with 2% of vaccinees developed skin rash. No vesicular rash was seen. Concomitant varicella vaccination did not significantly increase the incidences of reactions associated with MMR vaccine. The seroconversion rates to varicella, measles, mumps and rubella all approached 100%. This study confirmed that simultaneous administration of live attenuated varicella vaccine and MMR vaccine was safe and immiinogenic in healthy young children in Taiwan. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0031938459&partnerID=40&md5=810ee75bd6ec08a861b990147cb29d24 https://scholars.lib.ntu.edu.tw/handle/123456789/526492 |
ISSN: | 0001-6578 | SDG/關鍵字: | chickenpox vaccine; measles mumps rubella vaccine; unclassified drug; varicella zoster vaccine; anorexia; antibody response; article; chickenpox; child; clinical trial; diarrhea; drug efficacy; drug screening; fatigue; fever; human; immunogenicity; major clinical study; rash; seroconversion; vaccination; vomiting; Antibodies, Viral; Chickenpox Vaccine; Female; Humans; Infant; Male; Vaccines, Attenuated |
顯示於: | 醫學系 |
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