https://scholars.lib.ntu.edu.tw/handle/123456789/526817
標題: | Implementing the European Society of Cardiology 0-h/1-h algorithm in patients presenting very early after chest pain | 作者: | Shiozaki M. Inoue K. Suwa S. CHIEN-CHANG LEE Chiang S.-J. Sato A. Shimizu M. Fukuda K. Hiki M. Kubota N. Tamura H. Fujiwara Y. Ouchi S. Miyazaki T. Hirano Y. Tanaka H. Sugita M. Nakazato Y. Sumiyoshi M. Daida H. |
公開日期: | 2020 | 卷: | 320 | 起(迄)頁: | 1-6 | 來源出版物: | International Journal of Cardiology | 摘要: | Background: The European Society of Cardiology (ESC) recommends a 0-h/1-h (0/1-h) algorithm to classify patients with suspected non-ST-segment elevation myocardial infarction (NSTEMI). However, reliable evidence about patients who present early after the onset of symptoms is limited, likely because high-sensitivity cardiac troponin (hs-cTn) values cannot increase sufficiently within that time. This study aimed to evaluate the outcomes in real-world situations that utilized the 0/1-h algorithm. Methods: In a prospective, international, multicenter cohort study that enrolled 1638 patients presenting with acute chest pain to the emergency department, we assessed the performance of the 0/1-h algorithm using hs-cTnT and the associated 30-day rates of major adverse cardiac events: death and acute myocardial infarction (AMI). Results: Among 1074 patients, the prevalence of AMI was 16.0%. An approximately 60.1% (n = 645) of patients visited the hospital within 3 h after onset of chest pain (less than 1 h; 18.2% [n = 196], less than 2 h; 27.5% [n = 295], and less than 3 h; 14.3% [n = 154]). Moreover, the prevalence rates of AMI were similar at all times (1 h, 16.8%; 1–2 h, 20.7%; 2–3 h, 18.2%; p =.5). According to the ESC 0/1-h algorithm, the distribution patterns of rule-out, observe, and rule-in groups were similar; however, none of the patients was diagnosed with AMI or cardiac death in the rule-out group. Conclusion: This study revealed the applicability of the 0/1-h algorithm for the management of early presenters. ? 2020 Elsevier B.V. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/526817 | ISSN: | 0167-5273 | DOI: | 10.1016/j.ijcard.2020.07.037 | SDG/關鍵字: | acute heart infarction; aged; algorithm; Article; cardiology; cardiovascular mortality; cohort analysis; controlled study; emergency ward; female; heart death; hospital; human; major adverse cardiac event; major clinical study; male; medical society; prevalence; priority journal; prospective study; thorax pain; algorithm; clinical trial; hospital emergency service; multicenter study; thorax pain; biological marker; troponin T; Algorithms; Biomarkers; Cardiology; Chest Pain; Cohort Studies; Emergency Service, Hospital; Humans; Prospective Studies; Troponin T |
顯示於: | 醫學院附設醫院 (臺大醫院) |
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