https://scholars.lib.ntu.edu.tw/handle/123456789/527442
標題: | Hemophagocytic syndrome associated with antiepileptic drug | 作者: | Yang Y.-C. SHIANN-TANG JOU Chang Y.-H. Liang J.-S. WANG-TSO LEE |
公開日期: | 2004 | 卷: | 30 | 期: | 5 | 起(迄)頁: | 358-360 | 來源出版物: | Pediatric Neurology | 摘要: | An 8-year-3-month-old male with right porencephaly and epilepsy was found to have skin rash 2 weeks after the beginning of treatment with lamotrigine. One month later he suffered from impaired liver function and pancytopenia in the presence of hypocellular bone marrow with hemophagocytosis. No evidence of infection was evident. Intravenous immunoglobulin and steroid were administered with discontinuation of lamotrigine; the hemogram and liver function profile improved dramatically. Hemophagocytic syndrome should be considered a possible cause of pancytopenia in patients taking new antiepileptic drugs such as lamotrigine. ? 2004 by Elsevier Inc. All rights reserved. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-2542452881&doi=10.1016%2fj.pediatrneurol.2003.12.012&partnerID=40&md5=596c6d256a42e36422ddbb6375d81465 https://scholars.lib.ntu.edu.tw/handle/123456789/527442 |
ISSN: | 0887-8994 | DOI: | 10.1016/j.pediatrneurol.2003.12.012 | SDG/關鍵字: | anticonvulsive agent; immunoglobulin; lamotrigine; steroid; valproic acid; article; case report; clinical feature; disease association; epilepsy; hematology; hemophagocytic syndrome; human; liver dysfunction; liver function; male; pancytopenia; porencephaly; priority journal; rash; school child; tonic clonic seizure; treatment withdrawal; Anticonvulsants; Child; Histiocytosis, Non-Langerhans-Cell; Humans; Male; Triazines |
顯示於: | 醫學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。