https://scholars.lib.ntu.edu.tw/handle/123456789/528247
標題: | Presence of multidrug-resistant organisms in the residents and environments of long-term care facilities in Taiwan | 作者: | Lee C.-M. Lai C.-C. Chiang H.-T. Lu M.-C. Wang L.-F. Tsai T.-L. Kang M.-Y. Jan Y.-N. Lo Y.-T. Ko W.-C. Tseng S.-H. PO-REN HSUEH |
公開日期: | 2017 | 卷: | 50 | 期: | 2 | 起(迄)頁: | 133-144 | 來源出版物: | Journal of Microbiology, Immunology and Infection | 摘要: | Objectives This study investigated the prevalence of multidrug-resistant organisms (MDROs) in the residents and environments of long-term care facilities (LTCFs) in Taiwan. Methods We prospectively investigated the distribution of MDROs in residents of six LTCFs and their environments from January 2015 to December 2015 (intervention period). Active surveillance of colonization of MDROs was performed by culturing rectal and nasal swab samples every 3 months for the residents: 63, 79, and 73 in the first, second, and third surveillance investigations, respectively. If MDROs, including methicillin-resistant Staphylococcus aureus, carbapenem-resistant Enterobacteriaceae, carbapenem-resistant Pseudomonas aeruginosa, and MDR Acinetobacter baumannii were identified, then swab specimens from environmental sources were also collected and cultured. During the study period, several infection control measures were also implemented. Results The overall infection density decreased significantly from 2.69 per 1000 patient–days in the preintervention (January 2014 to December 2014) to 2.39 per 1000 patient–days during the intervention period (p?0.001). A total of 154 samples from residents and environmental sources were positive for MDROs. Methicillin-resistant S. aureus (n?=?83, 53.9%) was the predominant organism, followed by carbapenem-resistant Enterobacteriaceae (n?=?35, 22.7%), MDR A. baumannii (n?=?30, 19.5%), and carbapenem-resistant P. aeruginosa (n?=?6, 3.9%). The rates of detection of MDROs were 27.9% (60/215) in nasal swabs, 15.8% (34/215) in rectal swabs, and 11.1% (60/542) in the environmental sources. Conclusions The distribution and persistence of MDROs varied among the different LTCFs and time periods. ? 2017 |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/528247 | ISSN: | 1684-1182 | DOI: | 10.1016/j.jmii.2016.12.001 | SDG/關鍵字: | amikacin; antibiotic agent; cefepime; colistin; daptomycin; gentamicin; linezolid; meropenem; sultamicillin; teicoplanin; vancomycin; Acinetobacter infection; aged; antibiotic resistance; antibiotic sensitivity; Article; bacterial colonization; bacterial infection; bacterial skin disease; bacterium identification; bloodstream infection; carbapenem resistant Enterobacteriaceae; disease surveillance; female; human; infection control; long term care; major clinical study; male; methicillin resistant Staphylococcus aureus; methicillin resistant Staphylococcus aureus infection; multidrug resistance; nonhuman; nose smear; nursing home; nursing home patient; prevalence; prospective study; Pseudomonas infection; respiratory tract infection; soft tissue infection; Taiwan; urinary tract infection; very elderly; Acinetobacter baumannii; Bacterial Infections; bacterium; drug effects; Enterobacteriaceae; environmental microbiology; health care facility; heterozygote; isolation and purification; microbial sensitivity test; microbiology; molecular typing; multidrug resistance; nose mucosa; pathogenicity; Pseudomonas aeruginosa; rectum; statistics and numerical data; Acinetobacter baumannii; Aged; Aged, 80 and over; Bacteria; Bacterial Infections; Carrier State; Drug Resistance, Multiple, Bacterial; Enterobacteriaceae; Environmental Microbiology; Female; Health Facilities; Humans; Infection Control; Long-Term Care; Male; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Molecular Typing; Nasal Mucosa; Prevalence; Prospective Studies; Pseudomonas aeruginosa; Rectum; Taiwan |
顯示於: | 醫學院附設醫院 (臺大醫院) |
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