https://scholars.lib.ntu.edu.tw/handle/123456789/528356
標題: | Bacteria killing nanotechnology Bio-Kil effectively reduces bacterial burden in intensive care units | 作者: | PO-REN HSUEH Huang H.-C. Young T.-G. Su C.-Y. Liu C.-S. Yen M.-Y. |
公開日期: | 2014 | 卷: | 33 | 期: | 4 | 起(迄)頁: | 591-597 | 來源出版物: | European Journal of Clinical Microbiology and Infectious Diseases | 摘要: | A contaminated hospital environment has been identified as an important reservoir of pathogens causing healthcare-associated infections. This study is to evaluate the efficacy of bacteria killing nanotechnology Bio-Kil on reducing bacterial counts in an intensive care unit (ICU). Two single-bed rooms (S-19 and S-20) in the ICU were selected from 7 April to 27 May 2011. Ten sets of new textiles (pillow cases, bed sheets, duvet cover, and patient clothing) used by patients in the two single-bed rooms were provided by the sponsors. In the room S-20, the 10 sets of new textiles were washed with Bio-Kil; the room walls, ceiling, and air-conditioning filters were treated with Bio-Kil; and the surfaces of instruments (respirator, telephone, and computer) were covered with Bio-Kil-embedded silicon pads. Room S-19 served as the control. We compared the bacterial count on textiles and environment surfaces as well as air samples between the two rooms. A total of 1,364 samples from 22 different sites in each room were collected. The mean bacterial count on textiles and environmental surfaces in room S-20 was significantly lower than that in room S-19 (10.4 vs 49.6 colony-forming units [CFU]/100 cm2; P<0.001). Room S-20 had lower bacterial counts in air samples than room S-19 (33.4-37.6 vs 21.6-25.7 CFU/hour/plate; P<0.001). The density of microbial isolations was significantly greater among patients admitted to room S-19 than those to room S-20 (9.15 vs 5.88 isolates per 100 patient-days, P<0.05). Bio-Kil can significantly reduce bacterial burden in the environment of the ICU. ? 2013 Springer-Verlag. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/528356 | ISSN: | 0934-9723 | DOI: | 10.1007/s10096-013-1989-3 | SDG/關鍵字: | bio kill; disinfectant agent; unclassified drug; air sampling; article; Aspergillus; bacterial count; bacterial load; bactericidal activity; bacterium culture; bed; Candida; Clostridium difficile; environmental sanitation; hospital hygiene; human; intensive care unit; nanotechnology; priority journal; textile; devices; infection control; instrument sterilization; nanotechnology; procedures; Colony Count, Microbial; Humans; Infection Control; Intensive Care Units; Nanotechnology; Sterilization |
顯示於: | 醫學院附設醫院 (臺大醫院) |
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