https://scholars.lib.ntu.edu.tw/handle/123456789/528512
標題: | Outcomes of hospitalized patients with bacteraemic and non-bacteraemic community-acquired pneumonia caused by Streptococcus pneumoniae | 作者: | Lin S.-H. Lai C.-C. Tan C.-K. Liao W.-H. PO-REN HSUEH |
公開日期: | 2011 | 卷: | 139 | 期: | 9 | 起(迄)頁: | 1307-1316 | 來源出版物: | Epidemiology and Infection | 摘要: | In contrast to bacteraemic pneumococcal community-acquired pneumonia (CAP), there is a paucity of data on the clinical characteristics and outcomes of non-bacteraemic pneumococcal CAP. This retrospective study compared the outcome of hospitalized patients with bacteraemic and non-bacteraemic pneumococcal CAP treated at a medical centre from 2004 to 2008. Data on clinical outcomes including all-cause mortality, length of hospital stay, need for intensive-care unit admission and extrapulmonary involvement were analysed. In all, 221 patients with pneumococcal pneumonia (87 bacteraemic, 134 non-bacteraemic) were included. Patients with bacteraemic pneumococcal pneumonia (BPP) were older than those with non-BPP (46·2±30·7 years vs. 21·7±30·8 years, P<0·001) and were more likely to have underlying medical diseases (66·7% vs. 33·6%, P<0·001). The overall mortality rates at 7, 14, and 30 days were significantly higher in BPP than non-BPP patients (12·6% vs. 2·2%, 14·9% vs. 3·7%, 19·5% vs. 5·1%, all P<0·01). Multivariate logistic regression analysis showed that pneumococcal bacteraemia was correlated with extrapulmonary involvement (odds ratio 5·46, 95% confidence interval 1·97-15·16, P=0·001). In conclusion, S. pneumoniae bacteraemia increased the risk of mortality and extrapulmonary involvement in patients with pneumococcal CAP. ? Copyright Cambridge University Press 2010. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/528512 | ISSN: | 0950-2688 | DOI: | 10.1017/S0950268810002402 | SDG/關鍵字: | cefotaxime; chloramphenicol; clindamycin; erythromycin; levofloxacin; moxifloxacin; penicillin G; tetracycline; adolescent; adult; age distribution; aged; antibiotic sensitivity; antigen detection; article; bacteremia; bacterium isolate; child; community acquired pneumonia; comorbidity; controlled study; female; hospital patient; hospitalization; human; intensive care unit; length of stay; major clinical study; male; minimum inhibitory concentration; mortality; outcome assessment; preschool child; retrospective study; school child; sensitivity and specificity; Streptococcus pneumoniae; Adolescent; Adult; Aged; Bacteremia; Child; Child, Preschool; Community-Acquired Infections; Female; Hospital Mortality; Hospitalization; Humans; Length of Stay; Male; Middle Aged; Pneumonia, Pneumococcal; Retrospective Studies; Risk Factors; Severity of Illness Index; Streptococcus pneumoniae; Taiwan; Treatment Outcome |
顯示於: | 醫學院附設醫院 (臺大醫院) |
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