https://scholars.lib.ntu.edu.tw/handle/123456789/529388
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | Chen C.-H. | en_US |
dc.contributor.author | Shin S.D. | en_US |
dc.contributor.author | Sun J.-T. | en_US |
dc.contributor.author | Jamaluddin S.F. | en_US |
dc.contributor.author | Tanaka H. | en_US |
dc.contributor.author | Song K.J. | en_US |
dc.contributor.author | Kajino K. | en_US |
dc.contributor.author | Kimura A. | en_US |
dc.contributor.author | EDWARD PEI-CHUAN HUANG | en_US |
dc.contributor.author | MING-JU HSIEH | en_US |
dc.contributor.author | MATTHEW HUEI-MING MA | en_US |
dc.contributor.author | WEN-CHU CHIANG | en_US |
dc.date.accessioned | 2020-12-21T03:37:59Z | - |
dc.date.available | 2020-12-21T03:37:59Z | - |
dc.date.issued | 2020 | - |
dc.identifier.issn | 1549-1277 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/529388 | - |
dc.description.abstract | Whether rapid transportation can benefit patients with trauma remains controversial. We determined the association between prehospital time and outcome to explore the concept of the “golden hour” for injured patients. Methods and findings We conducted a retrospective cohort study of trauma patients transported from the scene to hospitals by emergency medical service (EMS) from January 1, 2016, to November 30, 2018, using data from the Pan-Asia Trauma Outcomes Study (PATOS) database. Prehospital time intervals were categorized into response time (RT), scene to hospital time (SH), and total prehospital time (TPT). The outcomes were 30-day mortality and functional status at hospital discharge. Multivariable logistic regression was used to investigate the association of prehospital time and outcomes to adjust for factors including age, sex, mechanism and type of injury, Injury Severity Score (ISS), Revised Trauma Score (RTS), and prehospital interventions. Overall, 24,365 patients from 4 countries (645 patients from Japan, 16,476 patients from Korea, 5,358 patients from Malaysia, and 1,886 patients from Taiwan) were included in the analysis. Among included patients, the median age was 45 years (lower quartile [Q1]–upper quartile [Q3]: 25–62), and 15,498 (63.6%) patients were male. Median (Q1–Q3) RT, SH, and TPT were 20 (Q1–Q3: 12–39), 21 (Q1–Q3: 16–29), and 47 (Q1–Q3: 32–60) minutes, respectively. In all, 280 patients (1.1%) died within 30 days after injury. Prehospital time intervals were not associated with 30-day mortality. The adjusted odds ratios (aORs) per 10 minutes of RT, SH, and TPT were 0.99 (95% CI 0.92–1.06, p = 0.740), 1.08 (95% CI 1.00–1.17, p = 0.065), and 1.03 (95% CI 0.98–1.09, p = 0.236), respectively. However, long prehospital time was detrimental to functional survival. The aORs of RT, SH, and TPT per 10-minute delay were 1.06 (95% CI 1.04–1.08, p < 0.001), 1.05 (95% CI 1.01–1.08, p = 0.007), and 1.06 (95% CI 1.04–1.08, p < 0.001), respectively. The key limitation of our study is the missing data inherent to the retrospective design. Another major limitation is the aggregate nature of the data from different countries and unaccounted confounders such as in-hospital management. Conclusions Longer prehospital time was not associated with an increased risk of 30-day mortality, but it may be associated with increased risk of poor functional outcomes in injured patients. This finding supports the concept of the “golden hour” for trauma patients during prehospital care in the countries studied. Copyright: ? 2020 Chen et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. | - |
dc.relation.ispartof | PLoS Medicine | - |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | adult; Article; breathing rate; clinical assessment; cohort analysis; emergency health service; emergency ward; female; Glasgow coma scale; health care concepts; hospital discharge; hospital management; human; injury; injury scale; major clinical study; male; medical record review; mortality rate; multicenter study; outcome assessment; patient transport; prehospital time; Rankin scale; receiver operating characteristic; resuscitation; retrospective study; revised trauma score; scoring system; structured questionnaire; systolic blood pressure; clinical trial; hospital; hospital emergency service; hospital mortality; injury; Japan; Malaysia; middle aged; odds ratio; organization and management; register; South Korea; statistical model; Taiwan; time factor; time to treatment; Adult; Cohort Studies; Emergency Medical Services; Emergency Service, Hospital; Female; Hospital Mortality; Hospitals; Humans; Injury Severity Score; Japan; Logistic Models; Malaysia; Male; Middle Aged; Odds Ratio; Registries; Republic of Korea; Retrospective Studies; Taiwan; Time Factors; Time-to-Treatment; Transportation of Patients; Trauma Centers; Wounds and Injuries | - |
dc.title | Association between prehospital time and outcome of trauma patients in 4 Asian countries: A cross-national, multicenter cohort study | en_US |
dc.identifier.doi | 10.1371/journal.pmed.1003360 | - |
dc.identifier.pmid | 33022018 | - |
dc.identifier.scopus | 2-s2.0-85092659144 | - |
dc.relation.journalvolume | 17 | - |
dc.relation.journalissue | 10 | - |
item.fulltext | no fulltext | - |
item.grantfulltext | none | - |
crisitem.author.dept | Emergency Medicine | - |
crisitem.author.dept | Emergency Medicine-NTUH | - |
crisitem.author.dept | Emergency Medicine-NTUHHC | - |
crisitem.author.dept | Emergency Medicine | - |
crisitem.author.dept | Emergency Medicine-NTUH | - |
crisitem.author.dept | Emergency Medicine | - |
crisitem.author.dept | Emergency Medicine-NTUH | - |
crisitem.author.dept | National Taiwan University Hospital Yun-Lin Branch | - |
crisitem.author.dept | Emergency Medicine | - |
crisitem.author.dept | Emergency Medicine-NTUH | - |
crisitem.author.dept | National Taiwan University Hospital Yun-Lin Branch | - |
crisitem.author.orcid | 0000-0002-4800-2561 | - |
crisitem.author.orcid | 0000-0003-3636-6250 | - |
crisitem.author.orcid | 0000-0002-4388-9984 | - |
crisitem.author.orcid | 0000-0001-8620-7982 | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | NTU Hsin-Chu Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
顯示於: | 醫學院附設醫院 (臺大醫院) |
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