|Title:||The angio-seal™ arterial closure device for early ambulation after elective percutaneous coronary intervention in patients receiving low-dose enoxaparin||Authors:||Lai Y.-C.
|Issue Date:||2008||Publisher:||Cambridge Medical Publications||Journal Volume:||36||Journal Issue:||5||Start page/Pages:||1077-1084||Source:||Journal of International Medical Research||Abstract:||
This study evaluated the efficacy and safety of use of the Angio-Seal? vascular closure device deployment for early ambulation (2 h) after elective percutaneous coronary intervention in 143 consecutive patients receiving either intravenous low-dose enoxaparin (0.5 mg/kg) or unfractionated heparin (UFH). The initial success rate of Angio-Seal? deployment was 98.6%, with no significant difference between the UFH group (98.9%) and the enoxaparin group (98.0%). In-hospital and clinic outcomes were evaluated in the 141 patients with successful Angio-Seal? deployment. During hospitalization, there were no deaths, myocardial infarction, urgent target vessel revascularization or bleeding events in either group; three patients in the UFH group and none in the enoxaparin group had minor vascular complications (differences not significant). In clinic follow-up, two patients in the UFH group and none in the enoxaparin group had major vascular complications (difference's not significant). Routine use of the Angio-Seal? for early ambulation in patients receiving intravenous low-dose enoxaparin compared with UFH provides promising efficacy and safety for daily practice. Copyright ? 2008 Field House Publishing LLP.
|ISSN:||0300-0605||DOI:||10.1177/147323000803600527||metadata.dc.subject.other:||acetylsalicylic acid; clopidogrel; enoxaparin; heparin; anticoagulant agent; drug derivative; enoxaparin; heparin; adult; article; clinical effectiveness; controlled study; drug dose titration; elective surgery; female; heart infarction; hemostasis; hospitalization; human; loading drug dose; low drug dose; major clinical study; male; mobilization; mortality; outcome assessment; percutaneous coronary intervention; revascularization; single drug dose; surgical instrument; thrombosis; aged; evaluation; femoral artery; hemostasis; instrumentation; middle aged; transluminal coronary angioplasty; treatment outcome; Aged; Angioplasty, Transluminal, Percutaneous Coronary; Anticoagulants; Early Ambulation; Enoxaparin; Femoral Artery; Hemostatic Techniques; Heparin; Humans; Male; Middle Aged; Treatment Outcome
|Appears in Collections:||醫學系|
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