https://scholars.lib.ntu.edu.tw/handle/123456789/533629
標題: | Long-term outcome of percutaneous coronary intervention for unprotected left main coronary artery disease | 作者: | Wu X.-M. Liu C.-P. Lin W.-C. HSIEN-LI KAO |
關鍵字: | Bifurcation lesions; Left main coronary artery disease; Percutaneous coronary intervention; Stents | 公開日期: | 2010 | 卷: | 138 | 期: | 3 | 起(迄)頁: | 272-276 | 來源出版物: | International Journal of Cardiology | 摘要: | Objectives: The aim of this study is to evaluate the in-hospital, 30?day and long-term outcomes after percutaneous coronary intervention for unprotected left main coronary artery disease. Backgrounds: Left main coronary artery (LMCA) diseases stenosis is a strong indication for coronary artery bypass grafting (CABG). With improved device technology, percutaneous coronary intervention (PCI) with drug-eluting stent (DES) stents had been recently advocated as an alternative procedure for the unprotected LMCA disease. Methods: Between January 2003 and February 2007, all unprotected LMCA PCI procedures were retrospectively collected. Outcomes were obtained by chart record review and telephone interview. Results: Fifty five consecutive patients with > 50% diameter stenosis of LMCA undergoing PCI were analyzed. Indications for a percutaneous strategy were prohibitive surgical risks, or patient/physician preference. The procedural success rate was 98%. 41 patients (75%) received DES implantation. The majority of cases (n = 33) were treated with a double-stent strategy. There were no in-hospital deaths. The clinical follow-up time was 867 ± 410?days (range 20-1715). 18 (29%) patients experienced major adverse cardiac events, including 3 (5%) deaths, 4 (7%) myocardial infarctions, and 12 (21.8%) target lesion revascularizations (TLR) during follow-up. Multivariate analysis revealed hyperlipidemia (Hazard ratio, HR = 6.2, p = 0.024) and bifurcation involvement (HR = 4.4, p = 0.008) were independent predictors for MACE. Conclusions: Our results showed that PCI with stenting was an acceptable treatment option for patients with LMCA stenosis. Involvement of the LMCA bifurcation remains a predictor for unfavorable outcome. ? 2008 Elsevier Ireland Ltd. All rights reserved. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-74449085876&doi=10.1016%2fj.ijcard.2008.08.016&partnerID=40&md5=66163dc6db77b71066c9afde7a223d27 https://scholars.lib.ntu.edu.tw/handle/123456789/533629 |
ISSN: | 0167-5273 | DOI: | 10.1016/j.ijcard.2008.08.016 | SDG/關鍵字: | paclitaxel; rapamycin; aged; article; bare metal stent; controlled study; coronary artery bifurcation; coronary artery bypass graft; coronary artery obstruction; coronary stent; drug eluting stent; female; follow up; heart infarction; human; hyperlipidemia; interview; left coronary artery; long term care; major clinical study; male; medical record review; outcome assessment; overall survival; patient attitude; percutaneous coronary intervention; percutaneous transluminal angioplasty; physician attitude; prediction; priority journal; retrospective study; revascularization; surgical risk; survival rate; telephone; Aged; Angioplasty, Transluminal, Percutaneous Coronary; Coronary Artery Disease; Coronary Restenosis; Databases, Factual; Drug-Eluting Stents; Female; Humans; Hyperlipidemias; Kaplan-Meiers Estimate; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Predictive Value of Tests; Prevalence; Retrospective Studies; Time Factors; Treatment Outcome |
顯示於: | 醫學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。