https://scholars.lib.ntu.edu.tw/handle/123456789/533911
標題: | Formulation of novel lipid-coated magnetic nanoparticles as the probe for in vivo imaging | 作者: | Huang, Huey-Chung PO-YUAN CHANG Chang, Karen Chen, Chao-Yu CHUNG-WU LIN JYH-HORNG CHEN CHUNG-YUAN MOU ZEE-FEN CHANG FU-HSIUNG CHANG |
公開日期: | 21-九月-2009 | 卷: | 16 | 期: | 1 | 來源出版物: | Journal of Biomedical Science | 摘要: | Application of superparamagnetic iron oxide nanoparticles (SPIOs) as the contrast agent has improved the quality of magnetic resonance (MR) imaging. Low efficiency of loading the commercially available iron oxide nanoparticles into cells and the cytotoxicity of previously formulated complexes limit their usage as the image probe. Here, we formulated new cationic lipid nanoparticles containing SPIOs feasible for in vivo imaging. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/533911 https://www.scopus.com/inward/record.uri?eid=2-s2.0-70350624421&doi=10.1186%2f1423-0127-16-86&partnerID=40&md5=2d509c271a8c6d164801b129229ea2dd |
ISSN: | 1423-0127 | DOI: | 10.1186/1423-0127-16-86 | SDG/關鍵字: | 1,2 dioleoyl 3 trimethylammoniopropane; ferric ferrocyanide; macrogol 2000; phosphatidylethanolamine; rhodamine; superparamagnetic iron oxide nanoparticle; 1,2 dioleoyl 3 trimethylammoniopropane; 1,2 distearyl 3 sn phosphatidylethanolamine; contrast medium; lipid; macrogol 2000; magnetic nanoparticle; nuclear magnetic resonance imaging agent; phosphatidylethanolamine; polymer; superparamagnetic iron oxide nanoparticle; unclassified drug; 1,2 dioleoyloxy 3 (trimethylammonium)propane; 1,2-dioleoyloxy-3-(trimethylammonium)propane; cation; contrast medium; diagnostic agent; dioleoyl phosphatidylethanolamine; ferric ion; ferric oxide; macrogol derivative; metal nanoparticle; monounsaturated fatty acid; phosphatidylethanolamine; polyethylene glycol distearoylphosphatidylethanolamine; polyethylene glycol-distearoylphosphatidylethanolamine; quaternary ammonium derivative; animal experiment; animal model; article; cell differentiation; controlled study; cytotoxicity; flow cytometry; fluorescence microscopy; human; human cell; laser Doppler flowmetry; light scattering; mechanical probe; micelle; mouse; nerve cell; nonhuman; nuclear magnetic resonance imaging; particle size; priority journal; surface charge; tumor cell; tumor growth; zeta potential; animal cell; Article; cancer cell line; cell growth; contrast enhancement; HeLa cell line; hydrophobicity; imaging; in vivo study; nanoprobe; nerve cell differentiation; nuclear magnetic resonance scanner; adenocarcinoma; animal; Bagg albino mouse; colorectal tumor; drug effect; evaluation; feasibility study; HeLa cell; male; neuroblastoma; pathology; prostate tumor; synthesis; transplantation; tumor cell line; Mus; Adenocarcinoma; Animals; Cations; Cell Differentiation; Cell Line, Tumor; Colorectal Neoplasms; Contrast Media; Fatty Acids, Monounsaturated; Feasibility Studies; Ferric Compounds; Hela Cells; Humans; Hydrophobicity; Magnetic Resonance Imaging; Male; Metal Nanoparticles; Mice; Mice, Inbred BALB C; Micelles; Neuroblastoma; Particle Size; Phosphatidylethanolamines; Polyethylene Glycols; Prostatic Neoplasms; Quaternary Ammonium Compounds; Rhodamines |
顯示於: | 醫學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。