https://scholars.lib.ntu.edu.tw/handle/123456789/535191
標題: | Secular trends of healthcare-associated infections at a teaching hospital in Taiwan, 1981-2007 | 作者: | YU-CHUNG CHUANG YEE-CHUN CHEN SHAN-CHWEN CHANG Sun C.-C. Chang Y.-Y. Chen M.-L. Hsu L.-Y. JANN-TAY WANG |
公開日期: | 2010 | 卷: | 76 | 期: | 2 | 起(迄)頁: | 143-149 | 來源出版物: | Journal of Hospital Infection | 摘要: | The National Taiwan University Hospital (NTUH) adopted international guidelines for surveillance and control of healthcare-associated infection (HCAI) in 1981. This report describes the secular trends in HCAI at the NTUH over the past 27 years according to site of infection, aetiological agents and control measures. Clinical and microbiological data were collected by infection prevention and control nurses using a standardised case-record form. Specific control programmes were implemented and/or intensified as needed. Poisson or negative binomial regression analysis was used to quantify time trends of the incidence of HCAI. The annual number of discharges increased from 25 074 to 91 234 with a parallel increase in the Charlson comorbidity index. Active HCAI surveillance and periodic feedback were associated with a marked decrease in surgical site infections from 1981 to 2007 (2.5 vs 0.5 episodes per 100 procedures, P< 0.0001). On the other hand, there was a 4.8-fold increase in bloodstream infections (BSIs) (0.39 vs 1.88 episodes per 100 discharges, P<0.0001). The average annual increase of pathogen-specific HCAI incidence during 1981-2007 was 11.4% for meticillin-resistant Staphylococcus aureus (MRSA), 75.4% for extensively drug-resistant A. baumannii (XDRAB), and 7.5% for Candida albicans (P<0.0001, respectively). The infection prevention and control programme was upgraded in 2004 by implementing annual, intensive, project-based control programmes, and decreases in rates of HCAI, BSI, MRSA and XDRAB were observed. This long term study demonstrates the need to couple surveillance of HCAI with focused control programmes. Hospitals must invest in adequate manpower to accomplish these goals. ? 2010 The Hospital Infection Society. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-77956170929&doi=10.1016%2fj.jhin.2010.05.001&partnerID=40&md5=2dbe7f52fd37400c2fc39c7e924743e8 https://scholars.lib.ntu.edu.tw/handle/123456789/535191 |
ISSN: | 0195-6701 | DOI: | 10.1016/j.jhin.2010.05.001 | SDG/關鍵字: | amikacin; cefepime; ceftazidime; ciprofloxacin; colistin; gentamicin; imipenem; piperacillin plus tazobactam; sulbactam; Acinetobacter baumannii; Acinetobacter infection; antibiotic resistance; antibiotic sensitivity; article; bloodstream infection; Candida albicans; candidiasis; Enterobacter; Enterococcus; Escherichia coli; health survey; hospital discharge; hospital infection; human; incidence; infection control; infection control practitioner; infection prevention; Klebsiella; major clinical study; medical record; methicillin resistant Staphylococcus aureus; methicillin resistant Staphylococcus aureus infection; nonhuman; Poisson distribution; Pseudomonas aeruginosa; regression analysis; surgical infection; Taiwan; teaching hospital; university hospital; Acinetobacter baumannii; Candida albicans; Cross Infection; Drug Resistance, Multiple, Bacterial; Hospitals, Teaching; Humans; Incidence; Infection Control; Methicillin-Resistant Staphylococcus aureus; Sepsis; Surgical Wound Infection; Taiwan |
顯示於: | 醫學系 |
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