https://scholars.lib.ntu.edu.tw/handle/123456789/535258
標題: | Cryptococcosis in solid-organ, hematopoietic stem cell, and tissue transplant recipients: Evidence-Based evolving trends | 作者: | HSIN-YUN SUN Wagener M.M. Singh N. |
公開日期: | 2009 | 卷: | 48 | 期: | 11 | 起(迄)頁: | 1566-1576 | 來源出版物: | Clinical Infectious Diseases | 摘要: | The impact of current transplantation practices on the characteristics of cryptococcosis in solid-organ transplant recipients is not well defined. The incidence of cryptococcal disease among solid-organ transplant recipients has remained unchanged; however, patients are less likely to present with central nervous system or disseminated disease and are more likely to have cryptococcosis limited to the lungs. Additionally, lipid formulations of amphotericin B are now used more frequently, whereas their use in combination with flucytosine has decreased. The overall mortality of cryptococcosis has significantly improved in the current era. Renal failure remains associated with poor outcome, whereas use of lipid formulations of amphotericin B is associated with a higher survival rate. Despite rare infectious complication, certain peculiar attributes of cryptococcal disease in hematopoietic stem cell recipients and tissue transplant recipients warrant recognition. ? 2009 by the Infectious Diseases Society of America. All rights reserved. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-66949141155&doi=10.1086%2f598936&partnerID=40&md5=24a5e64cc96fbef032efabcae91276ac https://scholars.lib.ntu.edu.tw/handle/123456789/535258 |
ISSN: | 1058-4838 | DOI: | 10.1086/598936 | SDG/關鍵字: | alemtuzumab; amphotericin B deoxycholate; amphotericin B lipid complex; azathioprine; busulfan; caspofungin; cyclophosphamide; cyclosporin A; etoposide; fluconazole; flucytosine; fludarabine; ketoconazole; melphalan; mycophenolic acid 2 morpholinoethyl ester; prednisone; rapamycin; tacrolimus; thiotepa; thymocyte antibody; amphotericin B; antifungal agent; cryptococcosis; drug use; evidence based practice; female; graft rejection; heart transplantation; hematopoietic stem cell; human; kidney failure; kidney transplantation; liver transplantation; lung transplantation; major clinical study; male; mortality; organ transplantation; outcome assessment; priority journal; prognosis; recipient; review; survival rate; tissue transplantation; article; chemically induced disorder; cryptococcosis; hematopoietic stem cell transplantation; middle aged; organ transplantation; tissue transplantation; Amphotericin B; Antifungal Agents; Cryptococcosis; Female; Hematopoietic Stem Cell Transplantation; Humans; Kidney Failure; Male; Middle Aged; Organ Transplantation; Tissue Transplantation |
顯示於: | 醫學系 |
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