https://scholars.lib.ntu.edu.tw/handle/123456789/535591
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | CHIEN-HUI WU | en_US |
dc.contributor.author | CHENG-MAW HO | en_US |
dc.contributor.author | JIA-HUEI TSAI | en_US |
dc.contributor.author | HSIN-YUN SUN | en_US |
dc.contributor.author | REY-HENG HU | en_US |
dc.contributor.author | PO-HUANG LEE | en_US |
dc.date.accessioned | 2020-12-29T08:11:12Z | - |
dc.date.available | 2020-12-29T08:11:12Z | - |
dc.date.issued | 2017 | - |
dc.identifier.issn | 1304-0855 | - |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85019255084&doi=10.6002%2fect.2015.0031&partnerID=40&md5=415ab72022af3aa524c1fc00f029f384 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/535591 | - |
dc.description.abstract | Chronic hepatitis in immunosuppressed patients because of infection with hepatitis E virus is increasingly recognized, but there is a paucity of knowledge about hepatitis E virus infection in solidorgan transplant recipients. Herein, we reported the first confirmatory case of hepatitis E virus genotype 4 infection in a 47-year-old woman who underwent a liver transplant recipient in Taiwan. The patient presented with unexplained hepatitis and severe jaundice. Hepatitis E virus RNA was present in serum and identified as the genotype 4 by reverse transcription polymerase chain reaction. Pathological findings revealed that prominent zone 3 canalicular and hepatocellular cholestasis with a few acidophilic bodies and giant cell transformation, which was typical of hepatitis E virus hepatitis. Even undergoing ribavirin treatment, she had worse cholestasis and recurrent urinary tract infections. She died from encephalopathy and sepsis 6 months after the initial presentation. So far, compared with genotype 3 hepatitis E virus hepatitis, genotype 4 hepatitis E virus infection in solidorgan transplant recipients has been reported less frequently in the literature, and that warrants further accumulation of experiences. ? Ba?kent University 2017 Printed in Turkey. All Rights Reserved. | - |
dc.publisher | Baskent University | - |
dc.relation.ispartof | Experimental and Clinical Transplantation | - |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | antibiotic agent; antifungal agent; antivirus agent; bilirubin; interferon; ribavirin; tacrolimus; virus RNA; virus RNA; adult; Article; case report; cause of death; female; fever; flu like syndrome; hepatitis C; hepatitis E; Hepatitis E virus; Hepatitis E virus genotype 4; human; human tissue; immunosuppressive treatment; intrahepatic cholestasis; jaundice; liver biopsy; liver cirrhosis; liver transplantation; middle aged; sepsis; urinary tract infection; adverse effects; biopsy; drug effects; fatality; genetics; genotype; hepatitis E; Hepatitis E virus; Hepatitis, Chronic; liver function test; liver transplantation; phenotype; predictive value; treatment outcome; virology; Antiviral Agents; Biopsy; Fatal Outcome; Female; Genotype; Hepatitis E; Hepatitis E virus; Hepatitis, Chronic; Humans; Liver Function Tests; Liver Transplantation; Middle Aged; Phenotype; Predictive Value of Tests; Ribavirin; RNA, Viral; Treatment Outcome | - |
dc.title | First case genotype 4 hepatitis e infection after a liver transplant | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.6002/ect.2015.0031 | - |
dc.identifier.pmid | 26221721 | - |
dc.identifier.scopus | 2-s2.0-85019255084 | - |
dc.relation.pages | 228-230 | - |
dc.relation.journalvolume | 15 | - |
dc.relation.journalissue | 2 | - |
item.cerifentitytype | Publications | - |
item.grantfulltext | none | - |
item.fulltext | no fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.openairetype | journal article | - |
crisitem.author.dept | Traumatology-NTUH | - |
crisitem.author.dept | Surgery-NTUH | - |
crisitem.author.dept | Surgery-NTUH | - |
crisitem.author.dept | Surgery | - |
crisitem.author.dept | Pathology | - |
crisitem.author.dept | Pathology-NTUH | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Surgery | - |
crisitem.author.dept | Surgery-NTUH | - |
crisitem.author.dept | Surgery | - |
crisitem.author.dept | Surgery-NTUH | - |
crisitem.author.orcid | 0000-0002-6382-1186 | - |
crisitem.author.orcid | 0000-0003-1874-7615 | - |
crisitem.author.orcid | 0000-0002-9620-0431 | - |
crisitem.author.orcid | 0000-0003-0074-7721 | - |
crisitem.author.orcid | 0000-0001-6709-031X | - |
crisitem.author.orcid | 0000-0001-5831-035X | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
顯示於: | 醫學系 |
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