https://scholars.lib.ntu.edu.tw/handle/123456789/535863
標題: | Prognosis of adult patients with bacteremia caused by extensively resistant Acinetobacter baumannii | 作者: | Tseng Y.-C. JANN-TAY WANG FE-LIN LIN WU YEE-CHUN CHEN WEI-CHU CHIE SHAN-CHWEN CHANG |
公開日期: | 2007 | 卷: | 59 | 期: | 2 | 起(迄)頁: | 181-190 | 來源出版物: | Diagnostic Microbiology and Infectious Disease | 摘要: | Nosocomial bacteremia caused by extensively resistant Acinetobacter baumannii (ERAB) is an emerging problem in Taiwanese hospitals. Accordingly, we retrospectively investigated the epidemiology and outcomes of adult patients with ERAB bacteremia (ERABB) after different treatments from January 2001 to September 2004 at the National Taiwan University Hospital, Taipei, Taiwan. A total of 56 adult patients with ERABB and without other simultaneous infections were enrolled. Demographic, clinical, and laboratory data were obtained from medical records. Clinical data included underlying diseases and conditions with onset within 7 days after ERABB, severity of ERABB, antibiotic regimens for ERABB, and clinical outcomes. Laboratory data included hemograms, liver function tests, renal function tests, and albumin levels. Coagulation profiles were obtained at ERABB onset and 7 days before and after onset. All 56 episodes of ERABB were hospital-acquired. Most patients had Acute Physiology Scores and Chronic Health Evaluation II scores ?17 (66.1%) and Pitt bacteremia score ?4 (66.1%). Many had comorbid diseases at ERABB onset. Crude mortality rates on days 2, 7, 15, 30, and at discharge were 23.2%, 30.4%, 37.5%, 48.2%, and 60.7%, respectively. High severity of ERABB (Pitt bacteremia score ?4) and presence of immunosuppression were the only 2 predictors for day 30 mortality (odds ratios of 18.53 and 8.06, respectively). Antibiotic regimens for ERABB did not have a significant influence on ERABB outcomes. ? 2007 Elsevier Inc. All rights reserved. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-34748907890&doi=10.1016%2fj.diagmicrobio.2007.04.024&partnerID=40&md5=b9a88d8be959af9306866974ae4d69fe https://scholars.lib.ntu.edu.tw/handle/123456789/535863 |
ISSN: | 0732-8893 | DOI: | 10.1016/j.diagmicrobio.2007.04.024 | SDG/關鍵字: | albumin; aminoglycoside antibiotic agent; antibiotic agent; imipenem; meropenem; sultamicillin; Acinetobacter baumannii; aged; antibiotic therapy; APACHE; article; bacteremia; blood clotting; comorbidity; disease severity; female; hospital infection; human; immune deficiency; kidney function test; liver function test; major clinical study; male; mortality; nonhuman; priority journal; prognosis; retrospective study; Taiwan; treatment outcome; Acinetobacter baumannii; Acinetobacter Infections; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteremia; Cross Infection; Drug Resistance, Multiple, Bacterial; Female; Hospitals, Teaching; Humans; Male; Middle Aged; Multivariate Analysis; Prognosis; Taiwan |
顯示於: | 醫學系 |
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