https://scholars.lib.ntu.edu.tw/handle/123456789/536399
標題: | Incremental changes in QRS duration predict mortality in patients with atrial fibrillation | 作者: | Lin Y.-J. YEN BIN LIU Chu C.-C. |
關鍵字: | Atrial fibrillation; Mortality; QRS duration | 公開日期: | 2009 | 卷: | 32 | 期: | 11 | 起(迄)頁: | 1388-1394 | 來源出版物: | PACE - Pacing and Clinical Electrophysiology | 摘要: | Background: The purpose of this study was to evaluate serial changes in QRS duration in the 12-lead electrocardiogram (ECG) and their prognostic value in patients with atrial fibrillation (AF). Methods: Retrospective evaluation of the 12-lead ECG was performed in 822 patients with AF. Inclusion criteria included AF in two sequential ECGs and an echocardiogram obtained within 7 days of the second ECG. The mean age of the 228 patients enrolled in the study was 71.2 ± 12.9 and 45.6% were females. Nearly half of the patients had hypertension (49.5%) and a history of heart failure (44.7%). The patients were followed for 21 ± 19 months, and the end point was all-cause mortality. Results: Cox proportional hazards analysis demonstrated that the independent predictors of mortality in AF patients were age, renal insufficiency, a history of stroke, heart rate, incremental QRS prolongation (P = 0.0418), and the absence of warfarin use. Patients with QRS prolongation >15 ms had a worse prognosis than those with QRS prolongation ?15 ms (P = 0.0019). Conclusions: A progressive increase in QRS duration predicted a poor prognosis in patients with AF in our study. A prospective study is needed to substantiate the prognostic value of QRS prolongation in AF patients. ? 2009, The Authors. Journal compilation. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-70350223827&doi=10.1111%2fj.1540-8159.2009.02508.x&partnerID=40&md5=3296ac205545f7e6258a1f92e05166d0 https://scholars.lib.ntu.edu.tw/handle/123456789/536399 |
ISSN: | 0147-8389 | DOI: | 10.1111/j.1540-8159.2009.02508.x | SDG/關鍵字: | acetylsalicylic acid; angiotensin receptor antagonist; beta adrenergic receptor blocking agent; calcium channel blocking agent; digoxin; dipeptidyl carboxypeptidase inhibitor; loop diuretic agent; nitrate; spironolactone; ticlopidine; warfarin; adult; aged; aging; anticoagulant therapy; article; congestive heart failure; coronary artery disease; echocardiography; electrocardiogram; female; heart atrium arrhythmia; heart atrium fibrillation; heart electrophysiology; heart failure; heart rate; human; hypertension; Kaplan Meier method; kidney failure; major clinical study; male; mortality; prediction; prognosis; proportional hazards model; QRS complex; reproducibility; retrospective study; stroke; survival rate; thromboembolism; validation study; Aged; Atrial Fibrillation; Diagnosis, Computer-Assisted; Electrocardiography; Female; Humans; Incidence; Male; Reproducibility of Results; Risk Assessment; Risk Factors; Sensitivity and Specificity; Survival Analysis; Survival Rate; Taiwan |
顯示於: | 醫學系 |
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