https://scholars.lib.ntu.edu.tw/handle/123456789/537123
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | Bu L.-N. | en_US |
dc.contributor.author | HUEY-LING CHEN | en_US |
dc.contributor.author | Chang C.-J. | en_US |
dc.contributor.author | YEN-HSUAN NI | en_US |
dc.contributor.author | HONG-YUAN HSU | en_US |
dc.contributor.author | HONG-SHIEE LAI | en_US |
dc.contributor.author | WEN-MING HSU | en_US |
dc.contributor.author | MEI-HWEI CHANG | en_US |
dc.creator | Bu L.-N.;Chen H.-L.;Chang C.-J.;Ni Y.-H.;Hsu H.-Y.;Lai H.-S.;Hsu W.-M.;Mei-Hwei Chang | - |
dc.date.accessioned | 2021-01-04T07:38:34Z | - |
dc.date.available | 2021-01-04T07:38:34Z | - |
dc.date.issued | 2003 | - |
dc.identifier.issn | 0022-3468 | - |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0037388861&doi=10.1053%2fjpsu.2003.50128&partnerID=40&md5=753be6ec1568ad059062c18a770fb486 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/537123 | - |
dc.description.abstract | Purpose: The aim of this study was to evaluate the efficacy of trimethoprim-sulfamethoxazole (TMP/SMZ) and neomycin as the prophylactic agents against the recurrence of cholangitis in children with biliary atresia (BA) after a Kasai portoenterostomy. Methods: Nineteen BA patients aged 0 to 2 years, who had one episode of cholangitis after a Kasai portoenterostomy, were recruited in this study. Patients were assigned randomly into 2 groups: one (9 cases) with TMP/SMZ (TMP 4 mg/kg/d and SMZ 20 mg/kg/d, divided in 2 doses) and the other (10 cases) with neomycin (25 mg/kg/d, qid, 4 days a week). Another 18 BA patients aged 0 to 2 years, with cholangitis but not put on long-term prophylaxis, served as the historical control group. Results: The mean prophylactic periods were 14.6 months and 14.7 months in the TMP/SMZ and neomycin groups. Patients who received prophylaxis with either TMP/SMZ or neomycin had lower recurrence rates of cholangitis than those in the control group (P = .042 and .011). There was no difference in the recurrence rates of cholangitis between the TMP/SMZ and neomycin groups (P = .641). The survival rates were higher in the TMP/SMZ and neomycin groups than in the control group (P = .09 and .018). Conclusions: Use of TMP/SMZ or neomycin is effective as a prophylactic agent against the recurrence of cholangitis after the Kasai portoenterostomy, but there is no difference in efficacy between these 2 regimens. Copyright 2003, Elsevier Science (USA). All rights reserved. | - |
dc.publisher | W.B. Saunders | - |
dc.relation.ispartof | Journal of Pediatric Surgery | - |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | cotrimoxazole; neomycin; analysis of variance; antibiotic prophylaxis; article; blood culture; cholangitis; clinical article; clinical trial; controlled clinical trial; controlled study; drug efficacy; female; follow up; human; infant; infection prevention; leukocyte count; liver function test; long term care; male; portoenterostomy; postoperative infection; preschool child; priority journal; randomized controlled trial; recurrent disease; survival rate; treatment outcome; urine culture | - |
dc.title | Prophylactic oral antibiotics in prevention of recurrent cholangitis after the Kasai portoenterostomy | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1053/jpsu.2003.50128 | - |
dc.identifier.pmid | 12677572 | - |
dc.identifier.scopus | 2-s2.0-0037388861 | - |
dc.relation.pages | 590-593 | - |
dc.relation.journalvolume | 38 | - |
dc.relation.journalissue | 4 | - |
item.openairetype | journal article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.fulltext | no fulltext | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
crisitem.author.dept | Medical Education and Bioethics | - |
crisitem.author.dept | Pediatrics-NTUH | - |
crisitem.author.dept | Pediatrics | - |
crisitem.author.dept | Pediatrics | - |
crisitem.author.dept | Pediatrics-NTUH | - |
crisitem.author.dept | Medical Education and Bioethics | - |
crisitem.author.dept | Pediatrics-NTUH | - |
crisitem.author.dept | Surgery | - |
crisitem.author.dept | Surgery-NTUH | - |
crisitem.author.dept | Surgery-NTUH | - |
crisitem.author.dept | Surgery | - |
crisitem.author.dept | Pediatrics-NTUH | - |
crisitem.author.dept | Pediatrics | - |
crisitem.author.orcid | 0000-0002-4074-5838 | - |
crisitem.author.orcid | 0000-0002-1158-5249 | - |
crisitem.author.orcid | 0000-0002-5720-4835 | - |
crisitem.author.orcid | 0000-0002-7958-2183 | - |
crisitem.author.orcid | 0000-0002-5145-9538 | - |
crisitem.author.orcid | 0000-0002-3648-9261 | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
顯示於: | 醫學系 |
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