https://scholars.lib.ntu.edu.tw/handle/123456789/539520
標題: | Burden of varicella in the Asia-Pacific region: a systematic literature review | 作者: | Goh A.E.N. Choi E.H. Chokephaibulkit K. Choudhury J. Kuter B. PING-ING LEE Marshall H. Kim J.O. Wolfson L.J. |
關鍵字: | Disease burden; epidemiology; national immunization program; vaccine; Varicella | 公開日期: | 2019 | 出版社: | Taylor and Francis Ltd | 卷: | 18 | 期: | 5 | 起(迄)頁: | 475-493 | 來源出版物: | Expert Review of Vaccines | 摘要: | Introduction: Varicella is a highly contagious infection that can lead to serious complications, particularly in high-risk groups; however, it is vaccine preventable. Disease awareness and understanding of the disease burden can strongly influence vaccine coverage. This review provides insight into the current epidemiology and the importance of varicella from both public health and economic perspectives across the Asia-Pacific (APAC) region. Areas covered: A systematic literature review was conducted to identify studies on the incidence, seroprevalence, fatality rate and complication rate of varicella. Economic burden studies were also captured. Altogether, 125 studies were identified across the region; these were supplemented by government reports (gray data). Reported vaccine coverage varied from 2.8% to 97%; a key influencing factor was inclusion of the varicella vaccine in national immunization programs. In general, varicella incidence in the unvaccinated population was highest in children ?5 years old and seroprevalence increased with age. Economic analyses highlighted the cost-saving potential of vaccination programs, especially from a societal perspective. Expert opinion: Varicella-related data varied greatly across the APAC region, highlighting the need to better understand the burden of varicella in this area, and particularly identified the need for better surveillance and reporting. ? 2019, ? 2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85065034060&doi=10.1080%2f14760584.2019.1594781&partnerID=40&md5=c185884649ccd70ae30ffbd284afa57a https://scholars.lib.ntu.edu.tw/handle/123456789/539520 |
ISSN: | 1476-0584 | DOI: | 10.1080/14760584.2019.1594781 | SDG/關鍵字: | chickenpox vaccine; abdominal pain; acute pancreatitis; awareness; bacterial infection; chickenpox; disease burden; disease surveillance; drowsiness; headache; hospitalization; human; incidence; Medline; mortality; pneumonia; preventive health service; priority journal; public health problem; Review; seroprevalence; skin infection; systematic review; vaccination; Asia; chickenpox; cost of illness; economics; Pacific islands; seroepidemiology; survival analysis; Asia; Chickenpox; Cost of Illness; Humans; Incidence; Pacific Islands; Seroepidemiologic Studies; Survival Analysis |
顯示於: | 醫學系 |
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