https://scholars.lib.ntu.edu.tw/handle/123456789/539538
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | Su W.-J. | en_US |
dc.contributor.author | Chan T.-C. | en_US |
dc.contributor.author | Chuang P.-H. | en_US |
dc.contributor.author | Liu Y.-L. | en_US |
dc.contributor.author | PING-ING LEE | en_US |
dc.contributor.author | Liu M.-T. | en_US |
dc.contributor.author | Chuang J.-H. | en_US |
dc.creator | Su W.-J.;Chan T.-C.;Chuang P.-H.;Liu Y.-L.;Ping-Ing Lee;Liu M.-T.;Chuang J.-H. | - |
dc.date.accessioned | 2021-01-07T06:08:46Z | - |
dc.date.available | 2021-01-07T06:08:46Z | - |
dc.date.issued | 2015 | - |
dc.identifier.issn | 1201-9712 | - |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84918562947&doi=10.1016%2fj.ijid.2014.11.011&partnerID=40&md5=7044dac6fa91bad362ff08d859038169 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/539538 | - |
dc.description.abstract | Objectives: We aimed to estimate the pooled vaccine effectiveness (VE) in children over five winters through data linkage of two existing surveillance systems. Methods: Five test-negative case-control studies were conducted from November to February during the 2004/2005 to 2008/2009 seasons. Sentinel physicians from the Viral Surveillance Network enrolled children aged 6-59 months with influenza-like illness to collect throat swabs. Through linking with a nationwide vaccination registry, we measured the VE with a logistic regression model adjusting for age, gender, and week of symptom onset. Both fixed-effects and random-effects models were used in the meta-analysis. Results: Four thousand four hundred and ninety-four subjects were included. The proportion of influenza test-positive subjects across the five seasons was 11.5% (132/1151), 7.2% (41/572), 23.9% (189/791), 6.6% (75/1135), and 11.2% (95/845), respectively. The pooled VE was 62% (95% confidence interval (CI) 48-83%) in both meta-analysis models. By age category, VE was 51% (95% CI 23-68%) for those aged 6-23 months and 75% (95% CI 60-84%) for those aged 24-59 months. Conclusions: Influenza vaccination provided measurable protection against laboratory-confirmed influenza among children aged 6-59 months despite variations in the vaccine match during the 2004/2005 to 2008/2009 influenza seasons in Taiwan. ? 2014 The Authors. | - |
dc.publisher | Elsevier | - |
dc.relation.ispartof | International Journal of Infectious Diseases | - |
dc.subject | Case-control studies; Influenza surveillance; Influenza vaccine effectiveness | - |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | influenza vaccine; influenza vaccine; age; Article; case control study; child; controlled study; disease surveillance; drug efficacy; female; flu like syndrome; gender; human; infant; infection prevention; influenza; influenza vaccination; major clinical study; male; meta analysis (topic); physician; preschool child; register; season; Taiwan; throat culture; virus isolation; winter; epidemiological monitoring; immunology; Influenza A virus; Influenza, Human; meta analysis; statistical model; Case-Control Studies; Child, Preschool; Epidemiological Monitoring; Female; Humans; Infant; Influenza A virus; Influenza Vaccines; Influenza, Human; Logistic Models; Male; Seasons; Taiwan | - |
dc.title | Estimating influenza vaccine effectiveness using routine surveillance data among children aged 6-59 months for five consecutive influenza seasons | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1016/j.ijid.2014.11.011 | - |
dc.identifier.pmid | 25462180 | - |
dc.identifier.scopus | 2-s2.0-84918562947 | - |
dc.relation.pages | 115-121 | - |
dc.relation.journalvolume | 30 | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.openairetype | journal article | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
item.fulltext | no fulltext | - |
crisitem.author.dept | Pediatrics | - |
crisitem.author.dept | Pediatrics-NTUH | - |
crisitem.author.orcid | 0000-0002-7299-2825 | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
顯示於: | 醫學系 |
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