https://scholars.lib.ntu.edu.tw/handle/123456789/540688
標題: | Sarcopenic obesity is closely associated with metabolic syndrome | 作者: | CHIA-WEN LU KUEN-CHEH YANG HAO-HSIANG CHANG Lee L.-T. Chen C.-Y. KUO-CHIN HUANG |
公開日期: | 2013 | 卷: | 7 | 期: | 4 | 起(迄)頁: | e301-e307 | 來源出版物: | Obesity Research and Clinical Practice | 摘要: | Objectives: Obesity is a risk factor for metabolic syndrome (MetS). We aimed to investigate whether sarcopenic obesity (SO) was associated with MetS. Methods: A total of 600 community-dwelling males and females aged 63.6 ± 10.1 years in Northern Taiwan were enrolled in this study. Sarcopenia was defined by the percentage of total skeletal mass (total skeletal muscle mass (kg)/weight (kg) × 100). Cut-offs were established at <37% in men and <27.6% in women using the bioelectrical impedance analysis (BIA) method. Obesity was defined as body mass index (BMI) ?25 kg/m2. MetS was defined by the consensus of National Cholesterol Education Program-Adult Treatment Panel III modified for Asians. The association between MetS and SO was examined using multivariate logistic regression analyses after controlling potential confounders. Results: The SO group demonstrated a higher risk for MetS (odds ratio [OR] 11.59 [95% confidence interval [CI] 6.72-19.98]) than the obese group (7.53 [4.01-14.14]) and sarcopenic group (1.98 [1.25-3.16]). The individual components including waist circumference, serum triglycerides, high-density lipoprotein cholesterol (HDL-C), and fasting serum glucose were independently associated with SO. Conclusion: SO is a major risk factor for MetS. The BIA method and BMI can easily identify subjects at high risk for MetS. The underlying mechanism for the relationship between SO and MetS warrants further research. ? 2012 Asian Oceanian Association for the Study of Obesity. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84880290634&doi=10.1016%2fj.orcp.2012.02.003&partnerID=40&md5=de82c838e63d70c040bb13d5d8b7e9ff https://scholars.lib.ntu.edu.tw/handle/123456789/540688 |
ISSN: | 1871-403X | DOI: | 10.1016/j.orcp.2012.02.003 | SDG/關鍵字: | glucose; high density lipoprotein cholesterol; triacylglycerol; adult; analysis; article; bioelectrical impedance analysis; body mass; body weight; bone mass; cholesterol blood level; disease association; female; glucose blood level; human; major clinical study; male; metabolic syndrome X; obesity; physical activity; priority journal; sarcopenia; skeletal muscle; triacylglycerol blood level; waist circumference; Aged; Blood Glucose; Body Mass Index; Cholesterol, HDL; Cholesterol, LDL; Cross-Sectional Studies; Female; Humans; Male; Metabolic Syndrome X; Middle Aged; Obesity; Risk Factors; Sarcopenia; Taiwan; Waist Circumference |
顯示於: | 醫學系 |
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