https://scholars.lib.ntu.edu.tw/handle/123456789/541019
標題: | Balloon Dilation With Adequate Duration Is Safer Than Sphincterotomy for Extracting Bile Duct Stones: A Systematic review and Meta-analyses | 作者: | WEI-CHIH LIAO YU-KANG TU MING-SHIANG WU HSIU-PO WANG Lin J. Leung J.W. KUO-LIONG CHIEN |
公開日期: | 2012 | 卷: | 10 | 期: | 10 | 起(迄)頁: | 1101-1109 | 來源出版物: | Clinical Gastroenterology and Hepatology | 摘要: | Background & Aims: Endoscopic sphincterotomy (EST) is the standard treatment for choledocholithiasis. Endoscopic papillary balloon dilation (EPBD) has a lower risk for bleeding than EST, but EPBD is reserved for patients with bleeding diathesis because some studies reported that it increases the risk for pancreatitis. A short dilation time (?1 minute) is therefore recommended to reduce pancreatitis. However, there is evidence for an inverse relationship between EPBD duration and pancreatitis, prompting reevaluation of the optimal duration and relative safety of EPBD vs EST. Methods: We systematically reviewed randomized controlled trials to compare long EPBD (>1 minute), short EPBD (?1 minute), and EST regarding pancreatitis and overall complications. In addition to pairwise meta-analyses, Bayesian network meta-analysis was undertaken to compare the 3 procedures together. Relation between duration and outcome was also analyzed by meta-regression. Results: Compared with EST, short EPBD had a higher risk for pancreatitis (odds ratio [OR] by traditional analysis, 3.87; 95% confidence interval, 1.08-13.84 and OR by network meta-analysis, 4.14; 95% credible interval, 1.58-12.56), but long EPBD did not pose a higher risk than EST (1.14, 0.56-2.35 and 1.07, 0.38-2.76). Long EPBD had a lower overall rate of complications than EST (0.61, 0.36-1.04 and 0.54, 0.20-1.36). In network meta-analysis, probabilities of being the safest treatment for long EPBD/short EPBD/EST regarding pancreatitis and overall complications were 43.9%/0.2%/55.9% and 90.3%/1.3%/8.4%, respectively. Conclusions: Duration of EPBD is inversely associated with pancreatitis risk. Currently recommended ?1-minute dilation actually increases pancreatitis. EPBD with adequate duration may be preferred over EST because of comparable pancreatitis but lower overall complication rates. ? 2012 AGA Institute. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84866464267&doi=10.1016%2fj.cgh.2012.05.017&partnerID=40&md5=067a8c6a3e5f89a9d6f52cc444de4e6c https://scholars.lib.ntu.edu.tw/handle/123456789/541019 |
ISSN: | 1542-3565 | DOI: | 10.1016/j.cgh.2012.05.017 | SDG/關鍵字: | article; balloon dilatation; bile duct stone; cholangitis; common bile duct stone; comparative effectiveness; endoscopic papillary balloon dilation; endoscopic sphincterotomy; endoscopic therapy; human; meta analysis; operation duration; outcome assessment; pancreatitis; postoperative complication; postoperative hemorrhage; recurrent disease; systematic review; thromboembolism; Endoscopy, Gastrointestinal; Gallstones; Humans; Pancreatitis; Randomized Controlled Trials as Topic; Risk Assessment; Time Factors |
顯示於: | 醫學系 |
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