https://scholars.lib.ntu.edu.tw/handle/123456789/541943
標題: | Correlations of metabolic components with prostate volume in middle-Aged men receiving health check-Up | 作者: | Yang T.-K. Woo P. Yang H.-J. HONG-CHIANG CHANG Hsieh J.-T. KUO-HOW HUANG |
公開日期: | 2016 | 出版社: | Public Library of Science | 卷: | 11 | 期: | 1 | 起(迄)頁: | A279 | 來源出版物: | PLoS ONE | 摘要: | Objectives To investigate the impact of metabolic components and body composition indices on prostate volume (PV) in a population of middle-Aged men receiving health check-ups. Methods Six hundred and sixteen men receiving health assessments were stratified to large and small prostates based on the cut-off of median PV. Their demographic data, health history, and international prostate symptoms scores (IPSS) were collected. Metabolic components and body composition indices were compared between subjects with large and small prostates. Moreover, the correlations between these parameters and PV were analyzed by multivariate logistic regression. Results The median PV was 27 mL and mean age was 54.8 years. Subjects with large PV were older (56.5 vs. 52.7 years) and had higher serum prostate specific antigen (PSA) level (1.73 vs. 0.96 ng/mL), higher IPSS score (8.37 vs. 6.16), and higher body fat, body mass, and waist circumference (all p<0.05). In multivariate analysis, age (OR, 2.45; 95%CI, 1.74- 3.45), serum PSA (OR, 2.75; 95%CI, 1.96-3.86), waist circumference (OR, 1.45; 95%CI, 1.02-2.07), fatness (OR, 1.47; 95%CI, 1.04-2.09), and body fat mass (OR, 1.43; 95%CI, 1.00-2.03) were significantly correlated with PV of study subjects. In subgroup analysis, raised waist circumference (OR, 1.89; 95%CI, 1.00-3.59) was the independent predictor of PV in subjects with bothersome lower urinary tract symptoms. Conclusions Several metabolic components and body composition indices are significantly associated with PV of middle-Aged men, including raised waist circumference, fatness, and body fat mass. Raised waist circumference is the only independent predictor of PV in middle-Aged men with bothersome LUTS. ? 2016 Yang et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84953861270&doi=10.1371%2fjournal.pone.0145050&partnerID=40&md5=3e581da74697843e4d9d73f2bc76acbb https://scholars.lib.ntu.edu.tw/handle/123456789/541943 |
ISSN: | 1932-6203 | DOI: | 10.1371/journal.pone.0145050 | SDG/關鍵字: | glucose; high density lipoprotein; prostate specific antigen; triacylglycerol; high density lipoprotein; prostate specific antigen; triacylglycerol; adult; age distribution; Article; body composition; body mass; body water; controlled study; elevated blood pressure; fat mass; glucose blood level; human; lipoprotein blood level; male; medical examination; metabolic parameters; middle aged; prospective study; prostate volume; triacylglycerol blood level; waist circumference; blood; hypertension; metabolic syndrome X; metabolism; multivariate analysis; obesity; organ size; pathology; physical examination; procedures; prostate; Prostatic Hyperplasia; risk assessment; risk factor; statistical model; statistics and numerical data; Body Composition; Humans; Hypertension; Lipoproteins, HDL; Logistic Models; Male; Metabolic Syndrome X; Middle Aged; Multivariate Analysis; Obesity; Organ Size; Physical Examination; Prostate; Prostate-Specific Antigen; Prostatic Hyperplasia; Risk Assessment; Risk Factors; Triglycerides; Waist Circumference |
顯示於: | 醫學系 |
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