https://scholars.lib.ntu.edu.tw/handle/123456789/541973
標題: | Metabolic syndrome associated with reduced lower urinary tract symptoms in middle-aged men receiving health checkup | 作者: | Yang T.-K. Hsieh J.-T. Chen S.-C. HONG-CHIANG CHANG Yang H.-J. KUO-HOW HUANG |
公開日期: | 2012 | 卷: | 80 | 期: | 5 | 起(迄)頁: | 1093-1097 | 來源出版物: | Urology | 摘要: | Objective: To investigate the impact of metabolic syndrome on lower urinary tract symptoms in a sample of middle-aged men receiving a health checkup. Methods: Subjects aged 45 years or older who voluntarily underwent a medical checkup were enrolled. Participant demographics and health history were collected by a self-administered questionnaire. All participants were stratified into 2 groups by the presence of metabolic syndrome, as defined according to the updated National Cholesterol Education Program's Adult Treatment Panel III. Prostate volume and prostate-specific antigen levels were used for subgroup analysis. Results: During January through December of 2010, 708 subjects with a mean age of 55.6 ± 9.72 years were enrolled into the study. Compared to the nonmetabolic syndrome group, the metabolic syndrome group had lower total international prostatic symptoms score (7.89 ± 6.63 vs 6.85 ± 6.52, P =.05) and lower severity of weak urinary stream (1.24 ± 1.60 vs 0.95 ± 1.50, P =.021). In the higher prostate volume group (prostate volume <30 mL), total international prostatic symptoms score, storage score, and urinary frequency, urgency and incomplete emptying were lower in men vs those without metabolic syndrome (all P <.05). The negative association between voiding score, severity of lower urinary tract symptoms, and metabolic syndrome became particularly pronounced as the number of metabolic syndrome factors increased (P for trend <.01). Conclusion: We confirmed that metabolic syndrome had favorable effects on lower urinary tract symptoms, including voiding and storage symptoms in healthy middle-aged men. This beneficial effect was most significant in men with enlarged prostate and/or high prostate specific antigen levels. ? 2012 Elsevier Inc. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84868122279&doi=10.1016%2fj.urology.2012.08.002&partnerID=40&md5=1371c8b85084dd93c2c96b8e19d6fbe8 https://scholars.lib.ntu.edu.tw/handle/123456789/541973 |
ISSN: | 0090-4295 | DOI: | 10.1016/j.urology.2012.08.002 | SDG/關鍵字: | prostate specific antigen; adult; article; controlled study; demography; disease association; disease severity; human; impaired bladder emptying; lower urinary tract symptom; major clinical study; male; metabolic syndrome X; periodic medical examination; priority journal; prostate hypertrophy; questionnaire; urinary frequency; urinary urgency; Disease Progression; Endosonography; Follow-Up Studies; Humans; Lower Urinary Tract Symptoms; Male; Mass Screening; Metabolic Syndrome X; Middle Aged; Prostate; Prostate-Specific Antigen; Prostatic Hyperplasia; Quality of Life; Questionnaires; Retrospective Studies; Urination |
顯示於: | 醫學系 |
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