https://scholars.lib.ntu.edu.tw/handle/123456789/544258
標題: | Impact of nocturia on symptom-specific quality of life among community-dwelling adults aged 40 years and older | 作者: | HONG-JENG YU Chen F.-Y. Huang P.-C. Chen, Tony Hsiu Hsi WEI-CHU CHIE Liu C.-Y. |
公開日期: | 2006 | 卷: | 67 | 期: | 4 | 起(迄)頁: | 713-718 | 來源出版物: | Urology | 摘要: | Objectives: To evaluate factors predicting the effect of nocturia in a community-based cohort of adults using a nocturia-specific quality-of-life (N-QOL) questionnaire. Methods: From October 2004 to February 2005, adults aged 40 years old or older living in Matsu, Taiwan and reporting nocturia of one episode or more per night were interviewed with a 12-item N-QOL questionnaire consisting of Sleep/Energy and Bother/Concern subscales. Univariate analyses were used to analyze the effects of demographic characteristics, frequency and duration of nocturia, and sleeping characteristics on the N-QOL score. Multiple linear regression analysis was used to identify factors predicting the N-QOL score. Results: A total of 663 adults completed this study (mean age 59.4 years). The average N-QOL scores (a lower score indicates worse QOL) were 91.4 ± 11.2, 83.7 ± 13.2, 77.6 ± 16.8, and 67.6 ± 21.2 for nocturia episodes of 1, 2, 3, and 4 or more per night, respectively (P <0.001). Men reported significantly lower N-QOL (85.6 ± 15.1 versus 88.9 ± 13.1, P = 0.003) and Bother/Concern subscale scores (42.0 ± 8.4 versus 44.0 ± 7.4, P <0.001), but not Energy/Sleep subscale scores (43.6 ± 7.8 versus 44.4 ± 7.3, P = 0.158) than women. On multiple linear regression analysis, increasing nocturia episodes (regression coefficient -6.2, 95% confidence interval -7.4 to -5.0), male sex (regression coefficient -3.5, 95% confidence interval -5.4 to -1.5), and degree of sleeping disturbance after nocturia (regression coefficient -4.5, 95% confidence interval -5.6 to -3.4) independently predicted a significantly lower N-QOL score. Conclusions: The results of our study have confirmed that nocturia has a more significant QOL impact when the patient has two or more episodes per night. Moreover, men experienced a greater impact from nocturia than women, particularly in the Bother/Concern domain. ? 2006 Elsevier Inc. All rights reserved. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-33646483091&doi=10.1016%2fj.urology.2005.10.054&partnerID=40&md5=148ac5afe9bb5f232fbca5dca0db1b3f https://scholars.lib.ntu.edu.tw/handle/123456789/544258 |
ISSN: | 0090-4295 | DOI: | 10.1016/j.urology.2005.10.054 | SDG/關鍵字: | adult; aged; article; community living; controlled study; disease classification; disease severity; energy; female; human; major clinical study; male; multiple linear regression analysis; nocturia; prediction; priority journal; quality of life; questionnaire; sex difference; sleep; statistical significance; Taiwan; Adult; Aged; Female; Humans; Male; Middle Aged; Quality of Life; Questionnaires; Urination Disorders |
顯示於: | 醫學系 |
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