https://scholars.lib.ntu.edu.tw/handle/123456789/546105
標題: | Depressed host immunity in a case of metachronous primary uterine papillary serous carcinoma and non-Hodgkin's lymphoma | 作者: | WEN-CHUN CHANG BOR-CHING SHEU RUEY-JIEN CHEN SONG-NAN CHOW Huang S.-C. |
公開日期: | 2004 | 卷: | 14 | 期: | 5 | 起(迄)頁: | 1030-1032 | 來源出版物: | International Journal of Gynecological Cancer | 摘要: | Metachronous primary malignant tumors of uterine papillary serous carcinoma (UPSC) and non-Hodgkin's lymphoma (NHL) are rare. UPSC is a clinically aggressive and morphologically distinctive variant of endometrial carcinoma. We describe the clinical features of a 63-year-old patient with UPSC that was found 2 years after chemotherapy for malignant lymphoma of neck, stage IV and 5 months after radiation therapy for recurrence. This patient had undergone staging surgery and postoperative radiation for UPSC. One month after completion of radiotherapy, the patient expired due to persistence of the disease. The association between host immunity and UPSC is rarely described in the literature. Immunological profiles of this patient, with compositional changes of natural killer, B, and T cell, dramatically altered the percentage of CD4+ T cell, CD8+ T cell, and CD4/CD8 ratio, signifying depressed host immunity. Immunological profile of this patient stressed the issue of depressed host immunity and associated malignancies. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-4544295681&doi=10.1111%2fj.1048-891X.2004.014547.x&partnerID=40&md5=7ee57b0e2feff54cc6e48433b23ab037 https://scholars.lib.ntu.edu.tw/handle/123456789/546105 |
ISSN: | 1048-891X | DOI: | 10.1111/j.1048-891X.2004.014547.x | SDG/關鍵字: | antineoplastic agent; CD4 antigen; CD8 antigen; adult; article; case report; clinical feature; disease association; endometrium carcinoma; female; flow cytometry; human; immunity; medical literature; natural killer cell; nonhodgkin lymphoma; papillary carcinoma; postoperative period; priority journal; recurrent disease; uterine papillary serous carcinoma; uterus carcinoma; Carcinoma, Papillary; Disease Progression; Female; Flow Cytometry; Humans; Immunocompromised Host; Killer Cells, Natural; Lymphoma, Non-Hodgkin; Middle Aged; Neoplasms, Second Primary; T-Lymphocytes; Uterine Neoplasms |
顯示於: | 醫學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。