https://scholars.lib.ntu.edu.tw/handle/123456789/549897
標題: | Changes in peripheral mitochondrial DNA copy number in metformin-treated women with polycystic ovary syndrome: a longitudinal study | 作者: | PO-KAI YANG Chou, Chia-Hong Chang, Chin-Hao SHEE-UAN CHEN HONG-NERNG HO MEI-JOU CHEN |
關鍵字: | 8-Hydroxy-2′-Deoxyguanosine; DNA mitochondrial; Female; Humans; Metformin; Polycystic ovary syndrome; Testosterone | 公開日期: | 13-七月-2020 | 出版社: | BMC | 卷: | 18 | 期: | 1 | 來源出版物: | Reproductive biology and endocrinology : RB&E | 摘要: | Patients with polycystic ovarian syndrome (PCOS) are associated with known alterations in mitochondria DNA copy number (mtDNA-CN). The aim of this study is to study the change in mtDNA-CN in patients with PCOS who were treated with metformin. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/549897 | ISSN: | 1477-7827 | DOI: | 10.1186/s12958-020-00629-5 | SDG/關鍵字: | 8 hydroxydeoxyguanosine; liver enzyme; metformin; mitochondrial DNA; testosterone; antidiabetic agent; metformin; mitochondrial DNA; adult; Article; blood pressure; clinical trial; cohort analysis; copy number variation; disorders of mitochondrial functions; female; free androgen index; human; longitudinal study; major clinical study; metabolic parameters; ovary polycystic disease; prospective study; testosterone blood level; adolescent; body mass; drug effect; genetics; insulin resistance; ovary polycystic disease; pathology; physiology; young adult; Adolescent; Adult; Body Mass Index; DNA Copy Number Variations; DNA, Mitochondrial; Female; Humans; Hypoglycemic Agents; Insulin Resistance; Longitudinal Studies; Metformin; Polycystic Ovary Syndrome; Young Adult |
顯示於: | 醫學系 |
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