https://scholars.lib.ntu.edu.tw/handle/123456789/550215
Title: | Changes in urodynamic parameters after tolterodine treatment for female overactive bladder syndrome with or without voiding dysfunction | Authors: | Wu W.-Y. Hsiao S.-M. TING-CHEN CHANG HO-HSIUNG LIN |
Issue Date: | 2011 | Journal Volume: | 37 | Journal Issue: | 5 | Start page/Pages: | 436-441 | Source: | Journal of Obstetrics and Gynaecology Research | Abstract: | Aim: To investigate changes in urodynamic parameters after tolterodine treatment for female overactive bladder syndrome, especially in patients with voiding dysfunction. Methods: Between January and December 2006, 44 patients were enrolled for six months of treatment with tolterodine. Pre-treatment and post-treatment urodynamic studies were scheduled for the enrolled patients. Results: Among the remaining 33 patients (11 dropped out), bladder capacity (P < 0.001) and post-void residual urine (P = 0.009) increased, and functional urethral length (P = 0.049) and pad weight test (P = 0.03) decreased after treatment. Besides this, detrusor pressure at maximal urine flow, functional urethral length, maximal urethral pressure and maximal urethral closure pressure were less affected by tolterodine in patients with voiding dysfunction, compared to those without voiding dysfunction. Conclusions: Tolterodine treatment increased bladder capacity and decreased urine leakage; however, some urodynamic parameters in patients with voiding dysfunction were less affected by tolterodine treatment. ? 2011 Japan Society of Obstetrics and Gynecology. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-79956097549&doi=10.1111%2fj.1447-0756.2010.01370.x&partnerID=40&md5=299abddb76c7a84499bd189ad473516e https://scholars.lib.ntu.edu.tw/handle/123456789/550215 |
ISSN: | 1341-8076 | DOI: | 10.1111/j.1447-0756.2010.01370.x | SDG/Keyword: | tolterodine; adult; aged; article; bladder capacity; bladder disease; clinical article; controlled study; detrusor muscle; female; human; micturition disorder; overactive bladder syndrome; postvoid residual urine volume; treatment duration; urethra pressure; urinary urgency; urine flow rate; urine volume; urodynamics; Adult; Aged; Benzhydryl Compounds; Cresols; Female; Humans; Middle Aged; Muscarinic Antagonists; Phenylpropanolamine; Treatment Outcome; Urinary Bladder, Overactive; Urination Disorders; Urodynamics |
Appears in Collections: | 醫學系 |
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