https://scholars.lib.ntu.edu.tw/handle/123456789/551404
標題: | Analysis of fine-needle aspiration cytology of the salivary gland | 作者: | I-SHIOW JAN Chung P.-F. Weng M.-H. Huang M.-S. Lee Y.-T. TSU-YAO CHENG JENG-YUH KO Kuo S.-H. |
公開日期: | 2008 | 卷: | 107 | 期: | 5 | 起(迄)頁: | 364-370 | 來源出版物: | Journal of the Formosan Medical Association | 摘要: | Background/purpose: Fine needle aspiration (FNA) cytology has been widely accepted as a safe method for diagnosis of salivary gland lesions. This study investigated the accuracy of FNA cytology of salivary gland lesions by correlation between histology and cytology. Methods: One hundred and thirty-one archived salivary gland FNA specimens collected between January 1994 and December 2002 from 131 patients were correlated with histopathology findings. The major reasons for false-negative and false-positive results in cytologic diagnosis were determined. Results: Considering the results of histopathology as the diagnostic standard, the sensitivity of FNA cytology in diagnosing malignancy was 74% (17/23) after excluding two cases which had a cytodiagnosis of suspicion of malignancy. Excluding eight cases that had a cytodiagnosis of suspicion of malignancy, the diagnostic specificity was 99% (97/98). There were six false-negative and one false-positive cases. Conclusion: This study demonstrated that FNA cytology of the salivary gland is a useful technique for diagnosis of salivary gland lesions. Inadequate labeling of the aspiration sites and insufficient cellularity were the most important factors that resulted in incorrect cytologic interpretation. ? 2008 Elsevier & Formosan Medical Association. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/551404 | ISSN: | 0929-6646 | DOI: | 10.1016/S0929-6646(08)60101-1 | SDG/關鍵字: | article; aspiration biopsy; benign tumor; cancer cytodiagnosis; controlled study; correlation analysis; cytopathology; diagnostic accuracy; diagnostic value; false negative result; false positive result; histopathology; human; human cell; human tissue; malignant neoplastic disease; salivary gland biopsy; salivary gland tumor; sensitivity and specificity |
顯示於: | 醫學院附設醫院 (臺大醫院) |
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