https://scholars.lib.ntu.edu.tw/handle/123456789/551479
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | Kung A.W.-C. | en_US |
dc.contributor.author | Rachman I.A. | en_US |
dc.contributor.author | Adam J.M.F. | en_US |
dc.contributor.author | Roeshadi D. | en_US |
dc.contributor.author | Torralba T. | en_US |
dc.contributor.author | Navarra S. | en_US |
dc.contributor.author | Gamilla Z. | en_US |
dc.contributor.author | Ca?ete A. | en_US |
dc.contributor.author | de la Rosa M. | en_US |
dc.contributor.author | KEH-SUNG TSAI | en_US |
dc.contributor.author | Lin H.-Y. | en_US |
dc.contributor.author | Soong Y.K. | en_US |
dc.contributor.author | Lan J.-L. | en_US |
dc.contributor.author | Hsu H.-C. | en_US |
dc.contributor.author | Tu S.-T. | en_US |
dc.contributor.author | Lin R.-M. | en_US |
dc.contributor.author | Yuktanandana P. | en_US |
dc.contributor.author | Songpatanasilp T. | en_US |
dc.contributor.author | Ngarmukos S. | en_US |
dc.contributor.author | Soontrapa S. | en_US |
dc.contributor.author | Soontrapa S. | en_US |
dc.contributor.author | Rojanasthien S. | en_US |
dc.contributor.author | Luevitoonvechkij S. | en_US |
dc.contributor.author | Leerapan T. | en_US |
dc.contributor.author | Albert A. | en_US |
dc.contributor.author | Vanbelle S. | en_US |
dc.creator | Kung A.W.-C.;Rachman I.A.;Adam J.M.F.;Roeshadi D.;Torralba T.;Navarra S.;Gamilla Z.;Ca?Ete A.;De La Rosa M.;Keh-Sung Tsai;Lin H.-Y.;Soong Y.K.;Lan J.-L.;Hsu H.-C.;Tu S.-T.;Lin R.-M.;Yuktanandana P.;Songpatanasilp T.;Ngarmukos S.;Soontrapa S.;Soontrapa S.;Rojanasthien S.;Luevitoonvechkij S.;Leerapan T.;Albert A.;Vanbelle S. | - |
dc.date.accessioned | 2021-03-10T08:55:54Z | - |
dc.date.available | 2021-03-10T08:55:54Z | - |
dc.date.issued | 2009 | - |
dc.identifier.issn | 1756-1841 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/551479 | - |
dc.description.abstract | Aim: his study assesses the impact of serum carboxy-terminal collagen crosslinks (CTX) bone marker feedback (BMF) on adherence to ibandronate treatment in Asian postmenopausal women with osteoporosis. Methods: This was a 12-month (6-monthly phased), randomized, prospective, open-label, multi-center study conducted in 596 (of 628 enrolled) postmenopausal women with osteoporosis (? 85 years old) who were na?ve, lapsed, or current bisphosphonate users. Patients were randomized into two arms: serum CTX BMF at 3 months versus no-BMF. Once-monthly 150 mg ibandronate tablet was administered for 12 months and adherence to therapy was assessed at 6 and 12 months. In addition, patient satisfaction and safety of ibandronate treatment were also assessed. Results: Serum CTX BMF at 3 months showed no impact on adherence. The proportions of adherent patients were comparable in the BMF versus no-BMF arms (92.6% vs. 96.0%, P = 0.16); overall, serum CTX levels were similar for adherent and non-adherent patients. However, BMF patients felt more informed about their osteoporosis (P < 0.001) and more satisfied (P < 0.01) than no-BMF patients. Conclusions: The Asian postmenopausal osteoporosis patients in this study had a high adherence rate to once-monthly ibandronate therapy. Use of serum CTX BMF had no further impact on increasing adherence, but increased treatment satisfaction. ? 2009 Asia Pacific League of Associations for Rheumatology and Blackwell Publishing Asia Pty Ltd. | - |
dc.relation.ispartof | International Journal of Rheumatic Diseases | - |
dc.subject | Adherence; Bone marker; Compliance; Feedback; Ibandronate; Osteoporosis | - |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | bisphosphonic acid derivative; carboxy terminal telopeptide; ibandronic acid; aged; article; Asian; blood sampling; cardiovascular disease; clinical trial; comparative study; connective tissue disease; controlled clinical trial; controlled study; drug safety; female; gastrointestinal disease; hematologic disease; human; ileus; infection; major clinical study; metabolic disorder; multicenter study; musculoskeletal disease; neurologic disease; open study; patient compliance; patient education; patient information; patient satisfaction; postmenopause; postmenopause osteoporosis; priority journal; protein blood level; psychopathy; randomized controlled trial; Administration, Oral; Aged; Aged, 80 and over; Asian Continental Ancestry Group; Biological Markers; Bone and Bones; Bone Density Conservation Agents; Diphosphonates; Female; Humans; Middle Aged; Osteoporosis, Postmenopausal; Patient Compliance; Patient Satisfaction | - |
dc.title | Impact of bone marker feedback on adherence to once monthly ibandronate for osteoporosis among Asian postmenopausal women | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1111/j.1756-185X.2009.01413.x | - |
dc.identifier.pmid | 20374349 | - |
dc.identifier.scopus | 2-s2.0-69149106711 | - |
dc.relation.pages | 216-224 | - |
dc.relation.journalvolume | 12 | - |
dc.relation.journalissue | 3 | - |
item.cerifentitytype | Publications | - |
item.fulltext | no fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.openairetype | journal article | - |
item.grantfulltext | none | - |
crisitem.author.dept | Laboratory Medicine | - |
crisitem.author.dept | Laboratory Medicine-NTUH | - |
crisitem.author.orcid | 0000-0001-8528-1566 | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
顯示於: | 醫學院附設醫院 (臺大醫院) |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。