|Title:||Risk of skin cancer among patients with chronic kidney disease treated with ultraviolet b phototherapy for uraemic pruritus: A nationwide cohort study||Authors:||Ko, Mei Ju
Wu, Hon Yen
Tsai, Wan Chuan
Hsu, Le Yin
Tsai, Ping Hsiu
|Keywords:||Chronic kidney disease | Skin cancer | Uraemic pruritus | UVB phototherapy||Issue Date:||1-Jan-2021||Journal Volume:||101||Journal Issue:||2||Source:||Acta Dermato-Venereologica||Abstract:||
© 2021, Medical Journals/Acta D-V. All rights reserved. The safety of ultraviolet B (UVB) phototherapy with respect to cutaneous carcinogenesis has not been established for patients with chronic kidney disease. To investigate this issue, a nationwide cohort study of 10,805 patients with advanced chronic kidney disease was conducted using data from the National Health Insurance of Taiwan, the Taiwan Cancer Registry, and the national death registry. After a median follow-up of 75 months, 16 of 2,161 patients in the UVB group and 63 of 8,644 patients in the non-UVB group developed skin cancers. Compared with the non-UVB group, patients in the UVB group did not show an increased risk of skin cancer (hazard ratio 1.066; 95% confidence interval 0.584–1.944), non-melanoma skin cancer (hazard ratio 1.067; 95% confidence interval 0.571–1.996), or cutaneous melanoma (hazard ratio 1.009; 95% confidence interval 0.115–8.879). In addition, patients who received more UVB phototherapy did not show an increased risk of skin cancer. UVB phototherapy appears to be a safe treatment for uraemic pruritus in patients with chronic kidney disease.
|Appears in Collections:||醫學院附設醫院 (臺大醫院)|
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