https://scholars.lib.ntu.edu.tw/handle/123456789/556841
標題: | Validation of the World Health Organization quality of life instrument in patients with HIV infection | 作者: | CHI-TAI FANG Hsiung P.-C. Yu C.-F. Chen M.-Y. Wang J.-D. |
公開日期: | 2002 | 卷: | 11 | 期: | 8 | 起(迄)頁: | 753-762 | 來源出版物: | Quality of Life Research | 摘要: | We studied the reliability and validity of the World Health Organization quality of life (WHOQOL) assessment instrument in patients with human immunodeficiency virus (HIV) infection. WHOQOL-BREF was used to assess 136 HIV-infected outpatients. The results were analyzed and compared with data from 213 healthy persons. The Cronbach's α for internal consistency ranged from 0.74 to 0.85 across domains in HIV-infected patients. The test-retest reliability ranged from 0.64 to 0.79 across domains at average 4-week retest interval. Factor analysis identified four major factors: social, psychological, environment, and physical, consistent with the four domains of the instrument. The scores of all four domains correlated positively with self-evaluated health status and happiness (r range: 0.52-0.60 and 0.55-0.73 across domains, respectively), and correlated negatively with the number and severity of symptoms (r range: -0.40 to -0.47 and -0.41 to -0.52, respectively). The scores of physical, psychological and social domains, but not the environment domain, discriminated between healthy persons and HIV-infected patients (all p < 0.01). We conclude that the WHOQOL-BREF can be a useful quality-of-life instrument in patients with HIV infection. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0036891691&doi=10.1023%2fA%3a1020870402019&partnerID=40&md5=6f24934efd70f8c2adc056544da8b3c9 https://scholars.lib.ntu.edu.tw/handle/123456789/556841 |
ISSN: | 0962-9343 | DOI: | 10.1023/A:1020870402019 | SDG/關鍵字: | adult; article; controlled study; environmental factor; factorial analysis; female; health status; human; Human immunodeficiency virus infection; major clinical study; male; priority journal; psychological aspect; quality of life; questionnaire; reliability; self evaluation; social aspect; world health organization; world health organization quality of life; Adult; Female; Health Status; HIV Infections; Humans; Male; Quality of Life; Questionnaires; Sickness Impact Profile; Taiwan; World Health Organization |
顯示於: | 流行病學與預防醫學研究所 |
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